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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Transmembrane Transporters >Sodium Channel Inhibitor >Amiloride hydrochloride dihydrate

Amiloride hydrochloride dihydrate

Amiloride hydrochloride dihydrate Structure
  • ₹19863.88
  • Product name: Amiloride hydrochloride dihydrate
  • CAS: 17440-83-4
  • MF: C6H8ClN7O.HCl.2H2O
  • MW: 302.12
  • EINECS:620-474-8
  • MDL Number:
  • Synonyms:Modamide;AMILORIDE HCL DIHYDRATE;AMILORIDE HYDROCHLORIDE 2-HYDRATE;Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-, monohydrochloride, dihydrate;AMILORIDE HYDROCHLORIDE (500 MG);AMILORIDEHYDROCHLORIDE,USP;3,5-Diamino-N-(aminoiminomethyl)-6-chloropyrazinecarboxamide hydrochloride dihydrate;Amiloride hydrochloride dihydrate
Price1 Properties Safety Information Description
1 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 1G
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1839
  • Product descriptionAmiloride Hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹19863.88
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) PHR1839 Amiloride Hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹19863.88 2022-06-14 Buy

Properties

Melting point :>240℃
RTECS :UQ2275500
storage temp. :Store at -20°C
solubility :Slightly soluble in water and in anhydrous ethanol.
pka :8.7(at 25℃)
form :Solid
color :Off-white to yellow
Water Solubility :Soluble in water at 50mg/ml

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P321 Specific treatment (see … on this label).
P405 Store locked up.

Description

Amiloride hydrochloride dihydrate is used as a calcium channel and sodium channel protein inhibitor. It reduces electrical potential across tubular epithelium, inhibits angiogenesis and inhibits capillary morphogenesis completely and reversibly at approximately 130 ?M. Amiloride ? HCl is an inhibitor of Sodium/Potassium-ATPase Protein. Defines the I2A-amiloride sensitive and I2B-amiloride insensitive imidazoline binding Blocks TRPP3, acid sensing- (ASIC) and mechanogated membrane-ion channels, as well as the Na+/H+ exchanger. Also inhibits urokinase-type plasminogen activator (uPA); has no effect on tissue-type plasminogen activator.

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Suppliers and manufacturers

Anphar Laboratories Pvt Ltd Rivashaa Agrotech Biopharma Pvt. Ltd. A.J Chemicals CLEARSYNTH LABS LTD. Pharmaffiliates Analytics and Synthetics P. Ltd Rivashaa Agrotech Biopharma Pvt. Ltd. BAL PHARMA LIMITED Oceanic Pharmachem Pvt., Ltd. (OPPL) Prism Consultancy SynZeal Research Pvt Ltd