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3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide

3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide Structure
  • ₹13044.13 - ₹52620.33
  • Product name: 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide
  • CAS: 199666-03-0
  • MF: C17H15N3O6S2
  • MW: 421.45
  • EINECS:
  • MDL Number:MFCD11040807
  • Synonyms:Ro 61-8048, >=98%;RO61-80483,4-dimethoxy-N-(4-(3-nitrophenyl)thiazol-2-yl)Benzenesulfonamide;3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide RO61-8048;RO 61-8048 3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide;KMO Inhibitor I, Ro 61-8048 ;3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide;3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide;3,4-diMethoxy-N-(4-(3-nitrophenyl)thiazol-2-yl)benzenesulfonaMide
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0233
  • Product descriptionRo 61-8048 ≥98% (HPLC)
  • Packaging5MG
  • Price₹13044.13
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0233
  • Product descriptionRo 61-8048 ≥98% (HPLC)
  • Packaging25MG
  • Price₹52620.33
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML0233 Ro 61-8048 ≥98% (HPLC) 5MG ₹13044.13 2022-06-14 Buy
Sigma-Aldrich(India) SML0233 Ro 61-8048 ≥98% (HPLC) 25MG ₹52620.33 2022-06-14 Buy

Properties

Melting point :185℃
Boiling point :627.4±65.0 °C(Predicted)
Density :1.471±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. :2-8°C
solubility :DMSO: ≥15mg/mL
form :Yellow solid
pka :6.29±0.10(Predicted)
color :faint yellow to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The kynurenine pathway mediates the metabolism of L-tryptophan to NAD+ and is particularly important in neurophysiology. Ro 61-8048 is a potent inhibitor of kynurenine 3-hydroxylase (IC50 = 37 nM), preventing the conversion of kynurenine to 3-hydroxy kynurenine. Ro 61-8048 inhibition of kynurenine 3-hydroxylase reduces ischemia-mediated neuronal damage in tissues. Ro 61-8048 can be used in vivo by direct injection.

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Suppliers and manufacturers

career henan chemical co
3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide
₹1.00 /1ASSAYS
3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide CAS:199666-03-0
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