3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide
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- ₹13044.13 - ₹52620.33
- Product name: 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide
- CAS: 199666-03-0
- MF: C17H15N3O6S2
- MW: 421.45
- EINECS:
- MDL Number:MFCD11040807
- Synonyms:Ro 61-8048, >=98%;RO61-80483,4-dimethoxy-N-(4-(3-nitrophenyl)thiazol-2-yl)Benzenesulfonamide;3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide RO61-8048;RO 61-8048 3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide;KMO Inhibitor I, Ro 61-8048 ;3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide;3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide;3,4-diMethoxy-N-(4-(3-nitrophenyl)thiazol-2-yl)benzenesulfonaMide
2 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberSML0233
- Product descriptionRo 61-8048 ≥98% (HPLC)
- Packaging5MG
- Price₹13044.13
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML0233
- Product descriptionRo 61-8048 ≥98% (HPLC)
- Packaging25MG
- Price₹52620.33
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | SML0233 | Ro 61-8048 ≥98% (HPLC) | 5MG | ₹13044.13 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | SML0233 | Ro 61-8048 ≥98% (HPLC) | 25MG | ₹52620.33 | 2022-06-14 | Buy |
Properties
Melting point :185℃
Boiling point :627.4±65.0 °C(Predicted)
Density :1.471±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. :2-8°C
solubility :DMSO: ≥15mg/mL
form :Yellow solid
pka :6.29±0.10(Predicted)
color :faint yellow to yellow
Boiling point :627.4±65.0 °C(Predicted)
Density :1.471±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. :2-8°C
solubility :DMSO: ≥15mg/mL
form :Yellow solid
pka :6.29±0.10(Predicted)
color :faint yellow to yellow
Safety Information
Symbol(GHS): |
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Signal word: | Warning | |||||||||||||||||||||
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Description
The kynurenine pathway mediates the metabolism of L-tryptophan to NAD+ and is particularly important in neurophysiology. Ro 61-8048 is a potent inhibitor of kynurenine 3-hydroxylase (IC50 = 37 nM), preventing the conversion of kynurenine to 3-hydroxy kynurenine. Ro 61-8048 inhibition of kynurenine 3-hydroxylase reduces ischemia-mediated neuronal damage in tissues. Ro 61-8048 can be used in vivo by direct injection.Related product price
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Suppliers and manufacturers
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₹1.00 /1ASSAYS
3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide CAS:199666-03-0
3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide CAS:199666-03-0