DBeQ
|
- ₹7500 - ₹46509
- Product name: DBeQ
- CAS: 177355-84-9
- MF: C22H20N4
- MW: 340.42
- EINECS:
- MDL Number:MFCD03691820
- Synonyms:DBeQ;2,4-QuinazolinediaMine, N2,N4-bis(phenylMethyl)-;2,4-QuinazolinediaMine, N,N'-bis(phenylMethyl)-;JRF 12;N,N'-Dibenzylquinazoline-2,4-diamine;N2,N4-Dibenzylquinazoline-2,4-diamine;JRF;N,N'-Dibenzylquinazoline-2,4-diamine DBeQ
4 prices
Selected condition：
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- 100MG
- ManufacturerTCI Chemicals (India)
- Product numberD5476
- Product descriptionDBeQ
- Packaging25MG
- Price₹7500
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberD5476
- Product descriptionDBeQ
- Packaging100MG
- Price₹14800
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML0031
- Product descriptionDBeQ ≥98% (HPLC)
- Packaging25MG
- Price₹46509
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML0031
- Product descriptionDBeQ ≥98% (HPLC)
- Packaging5MG
- Price₹11499.6
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | D5476 | DBeQ | 25MG | ₹7500 | 2022-05-26 | Buy |
| TCI Chemicals (India) | D5476 | DBeQ | 100MG | ₹14800 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | SML0031 | DBeQ ≥98% (HPLC) | 25MG | ₹46509 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML0031 | DBeQ ≥98% (HPLC) | 5MG | ₹11499.6 | 2022-06-14 | Buy |
Properties
Melting point :149 °C
Boiling point :573.1±52.0 °C(Predicted)
Density :1.259±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: ≥20mg/mL
form :powder
pka :7.78±0.30(Predicted)
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
InChIKey :QAIMUUJJAJBPCL-UHFFFAOYSA-N
CAS DataBase Reference :177355-84-9
Boiling point :573.1±52.0 °C(Predicted)
Density :1.259±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: ≥20mg/mL
form :powder
pka :7.78±0.30(Predicted)
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
InChIKey :QAIMUUJJAJBPCL-UHFFFAOYSA-N
CAS DataBase Reference :177355-84-9
Safety Information
| Symbol(GHS): |
|
|||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||
| Precautionary statements: |
|
Description
The ATPase p97 is an ubiquitin-selective chaperone known to play a critical role in the degradation of misfolded membrane and secretory proteins and has been linked to various cellular processes that require unfolding and disassembly of protein complexes. DBeQ is a selective, reversible, and ATP-competitive inhibitor of the ATPase p97 (Ki = 3.2 μM; IC50 = 1.5 μM). It does not exhibit activity when tested against a panel 170 protein kinases at concentrations as high as 15 μM. At 10 μM it blocks endoplasmic reticulum-associated degradation, impairing the autophagy pathway and promoting the activation of caspase-3 and -7 in cancer cells.Related product price
- Givinostat (ITF2357)
₹13888.48-55727.1 - Fingolimod hydrochloride
₹7068.73-100932.3 - Ezetimibe
₹13314.75-22743.33
Suppliers and manufacturers
A.J Chemicals
TCI Chemicals (India) Pvt. Ltd.
ATK CHEMICAL COMPANY LIMITED
BOC Sciences
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd
TargetMol Chemicals Inc.
Dideu Industries Group Limited
Zhejiang J&C Biological Technology Co.,Limited