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D-ERYTHRO-SPHINGOSINE-1-PHOSPHATE

D-ERYTHRO-SPHINGOSINE-1-PHOSPHATE Structure
  • ₹21769.08 - ₹63261.3
  • Product name: D-ERYTHRO-SPHINGOSINE-1-PHOSPHATE
  • CAS: 26993-30-6
  • MF: C18H38NO5P
  • MW: 379.47
  • EINECS:
  • MDL Number:MFCD00270077
  • Synonyms:1-SPP;(E)-D-ERYTHRO-2-AMINO-1-(DIHYDROGENPHOSPHATE)-4-OCTADECENE-1,3-DIOL;D-ERYTHRO-DIHYDROSPHINGOSINE-1-PHOSPHATE;D-ERYTHRO-SPHINGOSINE-1-PHOSPHATE;SPHINGOSINE-1-PHOSPHATE, D-ERYTHRO;SPHINGOSINE-1-PHOSPHORIC ACID;SPHINGOSINE-1-PO4;SPN-1-P
4 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 1MG
  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product number73914
  • Product descriptionSphingosine 1-phosphate ≥98.0% (TLC)
  • Packaging1MG
  • Price₹21769.08
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number567727
  • Product descriptionD-erythro-Sphingosine-1-phosphate - CAS 26993-30-6 - Calbiochem A putative second messenger that mobilizes calcium from intracellular stores via an IP3-independent pathway.
  • Packaging1MG
  • Price₹22390
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberS9666
  • Product descriptionSphingosine 1-phosphate ≥95%, powder
  • Packaging1MG
  • Price₹36426.13
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number73914
  • Product descriptionSphingosine 1-phosphate ≥98.0% (TLC)
  • Packaging5MG
  • Price₹63261.3
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 73914 Sphingosine 1-phosphate ≥98.0% (TLC) 1MG ₹21769.08 2022-06-14 Buy
Sigma-Aldrich(India) 567727 D-erythro-Sphingosine-1-phosphate - CAS 26993-30-6 - Calbiochem A putative second messenger that mobilizes calcium from intracellular stores via an IP3-independent pathway. 1MG ₹22390 2022-06-14 Buy
Sigma-Aldrich(India) S9666 Sphingosine 1-phosphate ≥95%, powder 1MG ₹36426.13 2022-06-14 Buy
Sigma-Aldrich(India) 73914 Sphingosine 1-phosphate ≥98.0% (TLC) 5MG ₹63261.3 2022-06-14 Buy

Properties

Melting point :179-189°C
Boiling point :548.8±60.0 °C(Predicted)
Density :1.094±0.06 g/cm3(Predicted)
RTECS :RG2260500
storage temp. :-20°C
solubility :methanol: THF: water (6:3:1): >0.5 mg/mL
form :waxy solid
pka :1.76±0.10(Predicted)
color :yellow
Sensitive :Light Sensitive
Stability :Moisture, Temperature Sensitive; Hygroscopic
CAS DataBase Reference :26993-30-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.

Description

Sphingosine-1-phosphate (S1P) is the product of phosphorylation of sphingosine by sphingosine kinase. Like many products of sphingomyelin, it exhibits a wide range of biological activities. Not only does it enhance cell growth, but it can inhibit the normal apoptotic response to a variety of stimuli. The ability of PKC to block apoptosis is likely due to the formation of S1P. S1P stimulates MAPK and counteracts the ceramide-induced activation of SAPK and JNK. It also increases intracellular calcium levels by both the liberation of calcium from internal stores and through activation of a Gi protein-coupled receptor resulting in the opening of a cell surface calcium channel.

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