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ChemicalBook > Product Catalogue >API >Nervous system drugs >Other nervous system drugs >Methylphenidate hydrochloride

Methylphenidate hydrochloride

Methylphenidate hydrochloride Structure
  • ₹0
  • Product name: Methylphenidate hydrochloride
  • CAS: 298-59-9
  • MF: C14H20ClNO2
  • MW: 269.77
  • EINECS:206-065-3
  • MDL Number:MFCD00058191
  • Synonyms:METHYLPHENIDATE HYDROCHLORIDE;RITALIN HYDROCHLORIDE;2-piperidineaceticacid,alpha-phenyl-,methylester,hydrochloride ;meridilhydrochloride ;2-Piperidineaceticacid, a-phenyl-, Methyl ester,hydrochloride (1:1);Methylphenidate hydrochloride solution;Ritalin (Methylphenidate Hcl);methylalpha-phenyl-2-piperidineacetatehydrochloride
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :196-198?C
Flash point :9℃
storage temp. :Store at RT
solubility :Freely soluble in water, soluble in ethanol (96 per cent), slightly soluble in methylene chloride.
form :Powder
pka :8.9(at 25℃)
Water Solubility :Soluble to 50 mM in water and to 100 mM in ethanol
BCS Class :2
Stability :Stable. Combustible. Incompatible with strong oxidizing agents, alkalies, barbiturates.
InChI :InChI=1S/C14H19NO2.ClH/c1-17-14(16)13(11-7-3-2-4-8-11)12-9-5-6-10-15-12;/h2-4,7-8,12-13,15H,5-6,9-10H2,1H3;1H
InChIKey :JUMYIBMBTDDLNG-UHFFFAOYSA-N
SMILES :C(C(=O)OC)(C1NCCCC1)C1C=CC=CC=1.Cl
CAS DataBase Reference :298-59-9(CAS DataBase Reference)
EPA Substance Registry System :Methylphenidate hydrochloride (298-59-9)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger GHS hazard pictograms P261, P285, P304+P341, P342+P311,P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P284 Wear respiratory protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501 Dispose of contents/container to..…

Description

Methylphenidate (a.k.a., Ritalin) is a schedule II drug in the United States commonly used as a psychostimulant for the treatment of attention-deficit hyperactivity disorder. It blocks dopamine and norepinephrine transporters as well as facilitates NMDA-receptor mediated synaptic transmission through σ1 receptors via PLC/PKC signaling. This interaction with the σ1 receptor has been suggested to underlie methylphenidate’s considerable abuse potential and potential psychiatric side effects. This product is intended for forensic and biological research applications.

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