ChemicalBook > Product Catalog >API >Nervous system drugs >Other nervous system drugs >Methylphenidate hydrochloride
Methylphenidate hydrochloride
- CAS No.
- 298-59-9
- Chemical Name:
- Methylphenidate hydrochloride
- Synonyms
- METHYLPHENIDATE HCL;Concerta;methylphenidate hydrochloride methanol*solution;Equasym;Metadate;Centedin;Centedrin;Centedrine;NSC 169868;Ciba 4311b
- CBNumber:
- CB0188559
- Molecular Formula:
- C14H20ClNO2
- Molecular Weight:
- 269.77
- MOL File:
- 298-59-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/1/17 16:57:51
| Melting point | 196-198?C |
|---|---|
| Flash point | 9℃ |
| storage temp. | Store at RT |
| solubility | Freely soluble in water, soluble in ethanol (96 per cent), slightly soluble in methylene chloride. |
| form | Powder |
| pka | 8.9(at 25℃) |
| Water Solubility | Soluble to 50 mM in water and to 100 mM in ethanol |
| BCS Class | 2 |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents, alkalies, barbiturates. |
| InChI | InChI=1S/C14H19NO2.ClH/c1-17-14(16)13(11-7-3-2-4-8-11)12-9-5-6-10-15-12;/h2-4,7-8,12-13,15H,5-6,9-10H2,1H3;1H |
| InChIKey | JUMYIBMBTDDLNG-UHFFFAOYSA-N |
| SMILES | C(C(=O)OC)(C1NCCCC1)C1C=CC=CC=1.Cl |
| CAS DataBase Reference | 298-59-9(CAS DataBase Reference) |
| EPA Substance Registry System | Methylphenidate hydrochloride (298-59-9) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H302-H334 |
| Precautionary statements | P261-P264-P270-P284-P301+P312-P501 |
| Hazard Codes | Xn,T,F |
| Risk Statements | 22-42-39/23/24/25-23/24/25-11 |
| Safety Statements | 22-26-36-45-36/37-16 |
| RIDADR | 3249 |
| WGK Germany | 3 |
| RTECS | TM3850000 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| Toxicity | LD50 orally in mice: 190 mg/kg (Greenblatt, Osterberg) |
Methylphenidate hydrochloride Chemical Properties,Uses,Production
Chemical Properties
white crystalline powder
Uses
Controlled substance (stimulant). CNS stimulant. Four isomers of Methylphenidate are known to exist. One pair of threo isomers and one pair of erythro are distinguished, from which only d-threo-Methyl phenidate exhibits the pharmacologically usually desired effects.
General Description
Odorless white crystalline powder. Metallic taste. Solutions are acid to litmus. Absence of general acid/base catalysis.
Air & Water Reactions
Water soluble.
Reactivity Profile
Methylphenidate hydrochloride is incompatible with alkalis and solutions of barbiturates . Undergoes typical ester hydrolysis in aqueous solutions at 176°F.
Fire Hazard
Flash point data for Methylphenidate hydrochloride are not available; however, Methylphenidate hydrochloride is probably combustible.
Biological Activity
Psychomotor stimulant. Inhibitor of dopamine and noradrenalin transporters that increases the extracellular concentration of dopamine and noradrenalin. Increases locomotor activity in vivo .
Methylphenidate hydrochloride Preparation Products And Raw materials
Raw materials
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Global( 119)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Ipca Laboratories Ltd | +91-2262105000 +91-2262105000 | Maharashtra, India | 61 | 58 | Inquiry |
| Centaur Pharmaceuticals Pvt Ltd | +912266499100 | Mumbai, India | 33 | 58 | Inquiry |
| Malladi Drugs AND Pharmaceuticals Limited | +91-9004653310 +91-9003056437 | Tamil Nadu, India | 69 | 58 | Inquiry |
| Sun Pharmaceutical Industries Ltd | +91-2242244224 +91-2243244324 | Maharashtra, India | 108 | 58 | Inquiry |
| ZCL Chemicals Ltd | +91-2261539999 +91-2261539999 | Maharashtra, India | 53 | 58 | Inquiry |
| Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
| Cohance Lifesciences (Previously RA Chem Pharma Ltd) | +91-4044758595 +91-4044758595 | Telangana, India | 47 | 58 | Inquiry |
| OCEAN TRADING CORPORATION | +91(22) 24921669 | New Delhi, India | 6211 | 58 | Inquiry |
| Medilink Pharmachem | +91 (79) 3007-0133 | New Delhi, India | 424 | 50 | Inquiry |
| IPCA Laboratories Limited | +91 (22) 6210 5000 | New Delhi, India | 56 | 58 | Inquiry |
298-59-9(Methylphenidate hydrochloride)Related Search:
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METHYLPHENIDATE HYDROCHLORIDE
RITALIN HYDROCHLORIDE
2-piperidineaceticacid,alpha-phenyl-,methylester,hydrochloride
meridilhydrochloride
2-Piperidineaceticacid, a-phenyl-, Methyl ester,hydrochloride (1:1)
Methylphenidate hydrochloride solution
Ritalin (Methylphenidate Hcl)
methylalpha-phenyl-2-piperidineacetatehydrochloride
METHYLPHENIDATE HYDROCHLORIDE--DEA*SCHED
METHYLPHENIDATE HYDROCHLORIDE(RITALIN HYDROCHLORIDE)
threo-methyl α-phenyl-α-(2-piperidyl)acetate hydrochloride
METHYLPHENIDATEHYDROCHLORIDE,USP
2-Piperidineacetic acid, a-phenyl-, methyl ester, hydrochloride (6CI, 8CI, 9CI)
Centedrin
Centedrine
Metadate CD
Methyl a-phenyl-2-piperidineacetate hydrochloride
NSC 169868
Ritalin hydrochloride, threo-Methyl α-phenyl-α-(2-piperidyl)acetate hydrochloride
a-Phenyl-2-piperidineacetic Acid Methyl Ester Hydrochloride
Ciba 4311b
Equasym
Metadate
Methyl Phenidylacetate Hydrochloride
Methylphenidan Hydrochloride
Methyl phenyl(piperidin-2-yl)acetate hydrochloride
Centedin
Methylphenidate hydrochloride (ritalin)
Metilfenidat hydrochloride
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Threo-methylphenidate hydrochloride
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Methylphenidate HCl, 1.0 mg/mL as free base
Methylphenidate HCl (Racemic mixture)
Methylphenidate Hydrochloride (CII), USP
Methylphenidate Hydrochloride CII (125 mg)
Methylphenidate-d9 HCl
METHYL 2-PHENYL-2-(PIPERIDIN-2-YL)ACETATE HCL
JUMYIBMBTDDLNG-UHFFFAOYSA-N
Methylphenidate(Ritalin)
Ritalin Impurity 10
Methyl (2RS)-phenyl[(2RS)-piperidin-2-yl]acetate hydrochloride
Methylphenidate hydrochloride USP/EP/BP
Methylphenidate HydrochlorideQ: What is
Methylphenidate Hydrochloride Q: What is the CAS Number of
Methylphenidate Hydrochloride Q: What is the storage condition of
Methylphenidate Hydrochloride Q: What are the applications of
Methylphenidate Hydrochloride
Methyl (2RS)-phenyl[(2SR)-piperidin-2-yl]acetate Hydrochloride
METHYLPHENIDATE HCL
methylphenidate hydrochloride methanol*solution
Concerta
Amylmetacresol Impurity 12
298-59-9
C14H19NO2HCl
C14H19NO2ClH
Heterocyclic Compounds
Aromatics
Intermediates & Fine Chemicals
Pharmaceuticals
ASACOL
298-59-9