2-Cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl-2-propenamide
![2-Cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl-2-propenamide Structure](/CAS/GIF/304896-28-4.gif)
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- ₹3500 - ₹55185.85
- Product name: 2-Cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl-2-propenamide
- CAS: 304896-28-4
- MF: C23H13Cl2N3O2
- MW: 434.27
- EINECS:
- MDL Number:MFCD01909444
- Synonyms:2-Cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl-2-propenamide;AGK2;SIRT2 Inhibitor, AGK2;2-Cyano-3-(5-(2,5-dichlorophenyl)furan-2-yl)-N-(quinolin-5-yl)acrylamide;SIRT2 Inhibitor, AGK2 - CAS 304896-28-4 - Calbiochem;CS-2248;AGK2;AGK-2;AGK 2;2-Propenamide, 2-cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl-
6 prices
Selected condition：
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- 100MG
- ManufacturerTCI Chemicals (India)
- Product numberA3193
- Product descriptionAGK-2
- Packaging5MG
- Price₹3500
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberA3193
- Product descriptionAGK-2
- Packaging25MG
- Price₹9200
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberA3193
- Product descriptionAGK-2
- Packaging100MG
- Price₹34000
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number566324
- Product descriptionSIRT2 Inhibitor, AGK2 - CAS 304896-28-4 - Calbiochem The SIRT2 Inhibitor, AGK2, also referenced under CAS 304896-28-4, controls the biological activity of SIRT2. This small molecule/inhibitor is primaril
- Packaging5MG
- Price₹13100
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA8231
- Product descriptionAGK2 ≥97% (HPLC), powder
- Packaging5MG
- Price₹13964.25
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberA8231
- Product descriptionAGK2 ≥97% (HPLC), powder
- Packaging25MG
- Price₹55185.85
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | A3193 | AGK-2 | 5MG | ₹3500 | 2022-05-26 | Buy |
| TCI Chemicals (India) | A3193 | AGK-2 | 25MG | ₹9200 | 2022-05-26 | Buy |
| TCI Chemicals (India) | A3193 | AGK-2 | 100MG | ₹34000 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | 566324 | SIRT2 Inhibitor, AGK2 - CAS 304896-28-4 - Calbiochem The SIRT2 Inhibitor, AGK2, also referenced under CAS 304896-28-4, controls the biological activity of SIRT2. This small molecule/inhibitor is primaril | 5MG | ₹13100 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A8231 | AGK2 ≥97% (HPLC), powder | 5MG | ₹13964.25 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A8231 | AGK2 ≥97% (HPLC), powder | 25MG | ₹55185.85 | 2022-06-14 | Buy |
Properties
Boiling point :675.1±55.0 °C(Predicted)
Density :1.445±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: soluble2mg/mL, clear (warmed)
form :Yellow solid
pka :8.87±0.43(Predicted)
color :White to Yellow to Orange
Density :1.445±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: soluble2mg/mL, clear (warmed)
form :Yellow solid
pka :8.87±0.43(Predicted)
color :White to Yellow to Orange
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Mammalian sirtuin 2 (SIRT2) is a nicotinamide adenine dinucleotide-dependent histone deacetylase (HDAC) with roles in cell cycle progression and tumorigenesis. AGK2 is a cell-permeable, selective inhibitor of SIRT2 (IC50 = 3.5 μM) that minimally affects either SIRT1 or SIRT3 at 10-fold higher levels. It rescues dopamine neurons from α-synuclein toxicity in both in vitro and in vivo Parkinson’s disease models, mimicking the effect of siRNA-mediated blockade of SIRT2 expression. AGK2 may be a useful tool for studying the roles of SIRT2 in neurodegeneration and aging, as well as cell cycle progression and tumorigenesis.More related product prices
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Suppliers and manufacturers
career henan chemical co
![2-Cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl-2-propenamide](https://img.chemicalbook.com/ProductImageEN/2020-2/small/41e91511-f58c-41bc-ab13-491db11871b1.jpg)
A.J Chemicals
TCI Chemicals (India) Pvt. Ltd.
ATK CHEMICAL COMPANY LIMITED
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd
Dideu Industries Group Limited
InvivoChem
Nantong HI-FUTURE Biology Co., Ltd.
TargetMol Chemicals Inc.
₹3.00 /1KG
2-Cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl-2-propenamide CAS:304896-28-4
2-Cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl-2-propenamide CAS:304896-28-4