SIRTINOL
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- ₹9612.6 - ₹36545.2
- Product name: SIRTINOL
- CAS: 410536-97-9
- MF: C26H22N2O2
- MW: 394.47
- EINECS:
- MDL Number:MFCD00810186
- Synonyms:2-[(2-HYDROXYNAPHTHALEN-1-YLMETHYLENE)AMINO]-N-(1-PHENETHYL)BENZAMIDE;SIRTINOL;SIR TWO INHIBITOR NAPHTHOL;(E)-2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-phenylethyl)benzamide;2-[[(2-Hydroxy-1-naphthalenyl)methylene]amino]-N-(1-phenylethyl)benzamide;2-{[(2-hydroxynaphthalen-1-yl)Methylidene]aMino}-N-(2-phenylethyl)benzaMide;{2-[(2-Hydroxynaphthalen-1-ylmethylene)amino]}-N-(1-phenethyl)benzamide (Sirtinol);Sirtinol - CAS 410536-97-9 - Calbiochem
3 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 1MG
- 5MG
- ManufacturerSigma-Aldrich(India)
- Product numberS7942
- Product descriptionSirtinol ≥95% (HPLC)
- Packaging5MG
- Price₹36545.2
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number566320
- Product descriptionSirtinol - CAS 410536-97-9 - Calbiochem A cell-permeable 2-hydroxy-1-naphthaldehyde derivative that acts as a specific and direct inhibitor of the sirtuin class of deacetylase activity with
- Packaging5MG
- Price₹28400.01
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberS7942
- Product descriptionSirtinol ≥95% (HPLC)
- Packaging1MG
- Price₹9612.6
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | S7942 | Sirtinol ≥95% (HPLC) | 5MG | ₹36545.2 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 566320 | Sirtinol - CAS 410536-97-9 - Calbiochem A cell-permeable 2-hydroxy-1-naphthaldehyde derivative that acts as a specific and direct inhibitor of the sirtuin class of deacetylase activity with | 5MG | ₹28400.01 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S7942 | Sirtinol ≥95% (HPLC) | 1MG | ₹9612.6 | 2022-06-14 | Buy |
Properties
Melting point :119-120℃
Boiling point :659.2±50.0 °C(Predicted)
Density :1.16
storage temp. :-20°C
solubility :Soluble in DMSO (up to 30 mg/ml).
form :Yellow solid
pka :7.85±0.50(Predicted)
color :Pale yellow
Water Solubility :Soluble in water, DMSO and methanol
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Boiling point :659.2±50.0 °C(Predicted)
Density :1.16
storage temp. :-20°C
solubility :Soluble in DMSO (up to 30 mg/ml).
form :Yellow solid
pka :7.85±0.50(Predicted)
color :Pale yellow
Water Solubility :Soluble in water, DMSO and methanol
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Safety Information
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Description
Sirtinol is a cell-permeable inhibitor of sirtuin NAD+-dependent deacetylases, inhibiting the yeast sirtuin Sir2p with an IC50 value of 68 μM and the human sirtuins SIRT1 and SIRT2 with IC50 values of 131 and 38 μM, respectively. It does not alter HDAC1 activity. Sirtinol inhibits the growth of cancer cells and suppresses inflammatory signaling in human dermal microvascular endothelial cells. In plants, sirtinol can be metabolized to 2-hydroxy-1-naphthoic acid, which activates auxin signaling and alters plant growth and development.Related product price
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