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4-Methoxy-N-(2,4,6-triMethylphenyl)benzenesulfonaMide, 97%

4-Methoxy-N-(2,4,6-triMethylphenyl)benzenesulfonaMide, 97% Structure
  • ₹8908 - ₹44339.2
  • Product name: 4-Methoxy-N-(2,4,6-triMethylphenyl)benzenesulfonaMide, 97%
  • CAS: 349085-82-1
  • MF: C16H19NO3S
  • MW: 305.39
  • EINECS:
  • MDL Number:MFCD02007969
  • Synonyms:4-Methoxy-N-(2,4,6-triMethylphenyl)benzenesulfonaMide, 97%;GSK137647A;GSK137647;4-Methoxy-N-(2,4,6-triMethylphenyl)benzenesulfonaMide,97%;GSK137647A;GSK-137647A;GSK 137647A;GSK-137647;GSK 137647;GSK137647A, >98%;CS-2460;FFA4 (GPR120) agonist GS137647A
4 prices
Selected condition:

Brand

  • ALFA India
  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • 250mg
  • 1g
  • ManufacturerALFA India
  • Product numberALF-H57808-MD
  • Product description4-Methoxy-N-(2,4,6-trimethylphenyl)benzenesulfonamide, 97%
  • Packaging250mg
  • Price₹8908
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-H57808-03
  • Product description4-Methoxy-N-(2,4,6-trimethylphenyl)benzenesulfonamide, 97%
  • Packaging1g
  • Price₹28340
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1152
  • Product descriptionGSK137647A ≥98% (HPLC)
  • Packaging5MG
  • Price₹11009.03
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1152
  • Product descriptionGSK137647A ≥98% (HPLC)
  • Packaging25MG
  • Price₹44339.2
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ALFA India ALF-H57808-MD 4-Methoxy-N-(2,4,6-trimethylphenyl)benzenesulfonamide, 97% 250mg ₹8908 2022-05-26 Buy
ALFA India ALF-H57808-03 4-Methoxy-N-(2,4,6-trimethylphenyl)benzenesulfonamide, 97% 1g ₹28340 2022-05-26 Buy
Sigma-Aldrich(India) SML1152 GSK137647A ≥98% (HPLC) 5MG ₹11009.03 2022-06-14 Buy
Sigma-Aldrich(India) SML1152 GSK137647A ≥98% (HPLC) 25MG ₹44339.2 2022-06-14 Buy

Properties

Boiling point :438.1±55.0 °C(Predicted)
Density :1.214±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble to 100 mM in DMSO and to 50 mM in ethanol.
form :powder
pka :9.23±0.10(Predicted)
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
CAS DataBase Reference :349085-82-1

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

GPR120 (Free Fatty Acid Receptor 4; FFAR4) is a G protein-coupled receptor expressed in intestine, adipocytes, and pro-inflammatory macrophages that is activated by long chain free fatty acids. GSK137647A is a diarylsulfonamide that acts as a selective agonist of GPR120 (pEC50s = 6.3, 6.2, and 6.1 at human, mouse, and rat receptors, respectively). It is selective for GPR120 over a panel of 61 other targets, including other FFARs. Like the natural GPR120 ligand linoleic acid, GSK137647A dose-dependently stimulates insulin secretion by mouse insulinoma MIN6 cells under high glucose conditions. It also modestly stimulates the production of glucagon-like peptide-1 in taste bud cells and human intestinal NCI-H716 cells.

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