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N-((S)-1-(4-((S)-2-(2,4-dichlorophenylsulfonaMido)-3-hydroxypropanoyl)piperazin-1-yl)-4-Methyl-1-oxopentan-2-yl)benzo[b]thiophene-2-carboxaMide

N-((S)-1-(4-((S)-2-(2,4-dichlorophenylsulfonaMido)-3-hydroxypropanoyl)piperazin-1-yl)-4-Methyl-1-oxopentan-2-yl)benzo[b]thiophene-2-carboxaMide Structure
  • ₹28491.4 - ₹111053.68
  • Product name: N-((S)-1-(4-((S)-2-(2,4-dichlorophenylsulfonaMido)-3-hydroxypropanoyl)piperazin-1-yl)-4-Methyl-1-oxopentan-2-yl)benzo[b]thiophene-2-carboxaMide
  • CAS: 942206-85-1
  • MF: C28H32Cl2N4O6S2
  • MW: 655.61
  • EINECS:
  • MDL Number:MFCD12912413
  • Synonyms:N-((S)-1-(4-((S)-2-(2,4-dichlorophenylsulfonaMido)-3-hydroxypropanoyl)piperazin-1-yl)-4-Methyl-1-oxopentan-2-yl)benzo[b]thiophene-2-carboxaMide;(N-((1S)-1-{[4-((2S)-2-{[(2,4-Dichlorophenyl)sulfonyl]amino}-3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide;GSK1016790A;GSK101;GSK1016790A;GSK-1016790A;GSK 1016790A;CS-2774;GSK-1016790A;GSK 1016790A;Benzo[b]thiophene-2-carboxamide, N-[(1S)-1-[[4-[(2S)-2-[[(2,4-dichlorophenyl)sulfonyl]amino]-3-hydroxy-1-oxopropyl]-1-piperazinyl]carbonyl]-3-methylbutyl]-
2 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberG0798
  • Product descriptionGSK1016790A ≥98% (HPLC)
  • Packaging10MG
  • Price₹28491.4
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberG0798
  • Product descriptionGSK1016790A ≥98% (HPLC)
  • Packaging50MG
  • Price₹111053.68
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) G0798 GSK1016790A ≥98% (HPLC) 10MG ₹28491.4 2022-06-14 Buy
Sigma-Aldrich(India) G0798 GSK1016790A ≥98% (HPLC) 50MG ₹111053.68 2022-06-14 Buy

Properties

Melting point :>119°C (dec.)
Density :1.426±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: >10mg/mL
form :white solid
pka :8.29±0.50(Predicted)
color :White to Off-White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.

Safety Information

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Signal word:
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Description

Transient receptor potential vanilloid 4 (TRPV4) is a nonselective cation channel thought to be involved in osmoregulation, hyperalgesia, and control of epithelial cell volume. GSK1016790A is a TRPV4 agonist that has been reported to elicit calcium influx in HEK cells expressing mouse or human TRPV4 (EC50s = 18 and 2.1 nM, respectively). It has been used to demonstrate a role for TRPV4 in regulating urinary bladder activity and endothelial control of vascular tone.

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