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ChemicalBook > Product Catalogue >API >Circulatory system drugs >Angina Pectoris Drugs >Nitrendipine

Nitrendipine

Nitrendipine Structure
  • ₹7945.55 - ₹93885.23
  • Product name: Nitrendipine
  • CAS: 39562-70-4
  • MF: C18H20N2O6
  • MW: 360.36
  • EINECS:254-513-1
  • MDL Number:MFCD00082255
  • Synonyms:NITRENDIPINE;1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylicacidethy ;baye5009 ;bayotensin ;baypress ;ethylmethyl1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxy ;2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylic acid methyl ethyl ester;Bylotensin
3 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 25MG
  • 100MG
  • 500MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberN144
  • Product descriptionNitrendipine >95%, powder
  • Packaging25MG
  • Price₹7945.55
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberN144
  • Product descriptionNitrendipine >95%, powder
  • Packaging100MG
  • Price₹28913.58
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberN144
  • Product descriptionNitrendipine >95%, powder
  • Packaging500MG
  • Price₹93885.23
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) N144 Nitrendipine >95%, powder 25MG ₹7945.55 2022-06-14 Buy
Sigma-Aldrich(India) N144 Nitrendipine >95%, powder 100MG ₹28913.58 2022-06-14 Buy
Sigma-Aldrich(India) N144 Nitrendipine >95%, powder 500MG ₹93885.23 2022-06-14 Buy

Properties

Melting point :1580C
Boiling point :492.4°C (rough estimate)
Density :1.3595 (rough estimate)
refractive index :1.5700 (estimate)
storage temp. :2-8°C
solubility :methanol: 15 mg/mL
form :powder
pka :2.79±0.70(Predicted)
color :yellow to green
Water Solubility :Soluble in DMSO (17.5 mg/ml), methanol (15 mg/ml), ethyl acetate, and ethanol (25 mM). Insoluble in water.
Stability :Stable for 1 year from date of purchase as supplied. Protect from light. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 week.
CAS DataBase Reference :39562-70-4(CAS DataBase Reference)
NIST Chemistry Reference :Nitrendipine(39562-70-4)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning GHS hazard pictograms P280,P302+P352, P312, P322, P363,P501
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P321 Specific treatment (see … on this label).

Description

Nitrendipine is a dihydropyridine used as an antihypertensive agent due to its ability to block L-type and T-type calcium channels, which play key roles in excitation-contraction coupling in cardiac and vascular smooth muscle cells, producing vasodilatory actions. It also binds to adenosine A1, A2A, and A3 receptors with Ki values of 8.96, 23.0, and 8.3 μM, respectively.

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