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ChemicalBook > Product Catalogue >API >Synthetic Anti-infective Drugs >Natural source of Anti-infectives >14-DEOXY-11,12-DIDEHYDROANDROGRAPHOLIDE

14-DEOXY-11,12-DIDEHYDROANDROGRAPHOLIDE

14-DEOXY-11,12-DIDEHYDROANDROGRAPHOLIDE Structure
  • ₹31533.23
  • Product name: 14-DEOXY-11,12-DIDEHYDROANDROGRAPHOLIDE
  • CAS: 42895-58-9
  • MF: C20H28O4
  • MW: 332.43
  • EINECS:226-852-5
  • MDL Number:MFCD07778081
  • Synonyms:14-DEOXY-11,12-DIDEHYDROANDROGRAPHOLIDE;3-[(1E)-2-[(1R,4aS,5R,6R,8aR)-Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethenyl]- 2(5H)-furanone;ent-(3β,11E)-3,19-Dihydroxy-8(17),11,13-labdatrien-16,15-olide;11,12-Didehydro-14-deoxyandrographolide;14-Deoxy-11,14-didehydroandrographolide;AP 10;Deoxy-11,12-Didehydroandrographolide, 14-;3-[(E)-2-[(1R,4aβ)-2-Methylene-5α-(hydroxymethyl)-5,8aα-dimethyl-6α-hydroxydecalin-1α-yl]ethenyl]-2,5-dihydrofuran-2-one
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Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product number55549
  • Product description14-Deoxy-11,12-didehydroandrographolide analytical standard
  • Packaging5MG
  • Price₹31533.23
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 55549 14-Deoxy-11,12-didehydroandrographolide analytical standard 5MG ₹31533.23 2022-06-14 Buy

Properties

Melting point :204-205℃
Boiling point :519.6±50.0 °C(Predicted)
Density :1.17
storage temp. :Store at -20°C
solubility :DMF: 10 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 2 mg/ml
pka :14.80±0.70(Predicted)
form :Solid
color :White to off-white

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
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Description

14-deoxy-11,12-didehydro Andrographolide is an analog of the natural diterpenoid andrographolide that can be isolated from A. paniculata. It retains the anti-inflammatory, antiallergenic, immuno-stimulatory, antiviral, antioxidant, hepatoprotective, and cardiovascular activities of andrographolide without producing cytotoxicity in KB cells (ED50 >20 μg/ml) that can occur with andrographolide 6.5 μg/ml.

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