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ARACHIDONIC ACID-(2-AMINOETHYL)-ESTER HYDROCHLORIDE

ARACHIDONIC ACID-(2-AMINOETHYL)-ESTER HYDROCHLORIDE Structure
  • ₹0
  • Product name: ARACHIDONIC ACID-(2-AMINOETHYL)-ESTER HYDROCHLORIDE
  • CAS: 443129-35-9
  • MF: C22H38ClNO2
  • MW: 384
  • EINECS:
  • MDL Number:MFCD05863982
  • Synonyms:O-(2-AMINOETHYL)-5Z,8Z,11Z,14Z-EICOSATETRAENESTER, MONOHYDROCHLORIDE;O-AEA H CL;O-AEA HYDROCHLORIDE;O-ARACHIDONOYLETHANOLAMINE HCL;O-ARACHIDONOYL ETHANOLAMINE HYDROCHLORIDE;VIRODHAMINE HYDROCHLORIDE;ARACHIDONIC ACID (2-AMINOETHYL)-ESTER HCL;ARACHIDONIC ACID-(2-AMINOETHYL)-ESTER HYDROCHLORIDE
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Properties

storage temp. :−70°C
solubility :DMF: ≥20 mg/mL, soluble
form :oil
color :pale yellow
Stability :Light Sensitive

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Arachidonoyl ethanolamide (AEA) was the first endogenous cannabinoid to be isolated and characterized as an agonist acting on the same receptors (CB1 and CB2) as tetrahydrocannabinols (THC). Since that time, a number of related endocannabinoids have been isolated, most notably 2-arachidonoyl glycerol (2-AG). O-Arachidonoyl ethanolamine hydrochloride (O-AEA) is a recently isolated constituent of human and rat brain wherein the ethanolamine moiety is attached “backwards”, as an ester instead of an amide, as in AEA. O-AEA has mixed agonist/antagonist activity at the CB1 receptor and does not appear to be the native endogenous cannabinoid agonist at this receptor. This is in keeping with other observations that 2-AG is the primary endogenous CB1 receptor ligand.

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