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ChemicalBook > Product Catalogue >API >Circulatory system drugs >Anti Shock vasoactive drugs >(R)-Phenylephrine Hydrochlorid

(R)-Phenylephrine Hydrochlorid

(R)-Phenylephrine Hydrochlorid Structure
  • ₹3600 - ₹51775.98
  • Product name: (R)-Phenylephrine Hydrochlorid
  • CAS: 61-76-7
  • MF: C9H13NO2.ClH
  • MW: 203.67
  • EINECS:200-517-3
  • MDL Number:MFCD00012605
  • Synonyms:(-)-3-[1(R)-Hydroxy-2-(methylamino)ethyl]phenol hydrochloride;Phenylephrine Hydrochloride (200 mg);PHENYLEPHRINE HCL BP ((R)-3-HYDROXY-ALPHA-(METHYLAMINO) METHYL] BENZENEMETHANOLHYDROCHL ORIDE);(-)-3-HYDROXY-ALPHA-(METHYLAMINOMETHYL)BENZYL ALCOHOL HYDROCHLORIDE;L-1-(M-HYDROXYPHENYL)-2-METHYLAMINOETHANOL HYDROCHLORIDE;L-(3-HYDROXYPHENYL)-N-METHYLETHANOLAMINEHYDROCHLORIDE;L-A-HYDROXY-B-METHYLAMINO-3-HYDROXY-1-ETHYLBENZENE HYDROCHLORIDE;L(-)-PHENYLEPHRINE HCL
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 500MG
  • 1ML
  • 5G
  • 10G
  • 25G
  • 50G
  • 1VIAL
  • 100G
  • ManufacturerTCI Chemicals (India)
  • Product numberP0398
  • Product description(R)-Phenylephrine Hydrochloride
  • Packaging5G
  • Price₹3600
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberP0398
  • Product description(R)-Phenylephrine Hydrochloride
  • Packaging25G
  • Price₹10800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP6126
  • Product description(R)-(−)-Phenylephrine hydrochloride powder
  • Packaging5G
  • Price₹6062
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1017
  • Product descriptionPhenylephrine Hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging500MG
  • Price₹9590.95
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product numberP-078
  • Product descriptionR-(-)-Phenylephrine hydrochloride solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant?
  • Packaging1ML
  • Price₹9921.8
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product numberP6126
  • Product description(R)-(−)-Phenylephrine hydrochloride powder
  • Packaging10G
  • Price₹9980.65
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product numberP8155
  • Product description(R)-(−)-Phenylephrine hydrochloride analytical standard
  • Packaging1VIAL
  • Price₹15793.68
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP6126
  • Product description(R)-(−)-Phenylephrine hydrochloride powder
  • Packaging25G
  • Price₹18662.3
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP6126
  • Product description(R)-(−)-Phenylephrine hydrochloride powder
  • Packaging50G
  • Price₹30981.15
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP6126
  • Product description(R)-(−)-Phenylephrine hydrochloride powder
  • Packaging100G
  • Price₹51775.98
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) P0398 (R)-Phenylephrine Hydrochloride 5G ₹3600 2022-05-26 Buy
TCI Chemicals (India) P0398 (R)-Phenylephrine Hydrochloride 25G ₹10800 2022-05-26 Buy
Sigma-Aldrich(India) P6126 (R)-(−)-Phenylephrine hydrochloride powder 5G ₹6062 2022-06-14 Buy
Sigma-Aldrich(India) PHR1017 Phenylephrine Hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material 500MG ₹9590.95 2022-06-14 Buy
Sigma-Aldrich(India) P-078 R-(-)-Phenylephrine hydrochloride solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant? 1ML ₹9921.8 2022-06-14 Buy
Sigma-Aldrich(India) P6126 (R)-(−)-Phenylephrine hydrochloride powder 10G ₹9980.65 2022-06-14 Buy
Sigma-Aldrich(India) P8155 (R)-(−)-Phenylephrine hydrochloride analytical standard 1VIAL ₹15793.68 2022-06-14 Buy
Sigma-Aldrich(India) P6126 (R)-(−)-Phenylephrine hydrochloride powder 25G ₹18662.3 2022-06-14 Buy
Sigma-Aldrich(India) P6126 (R)-(−)-Phenylephrine hydrochloride powder 50G ₹30981.15 2022-06-14 Buy
Sigma-Aldrich(India) P6126 (R)-(−)-Phenylephrine hydrochloride powder 100G ₹51775.98 2022-06-14 Buy

Properties

Melting point :143-145 °C(lit.)
alpha :-47 º (c=2, H2O)
refractive index :-45.5 ° (C=1, H2O)
Flash point :9℃
storage temp. :2-8°C
solubility :Freely soluble in water and in ethanol (96 per cent).
form :Crystalline Powder
pka :pK1 8.77; pK2 9.84(at 25℃)
color :White to almost white
PH :pH (10g/L, 25℃) : 4.5~5.5
Water Solubility :>=10 g/100 mL at 21 ºC
Merck :14,7286
BRN :4158948
Stability :Hygroscopic
LogP :-0.310
CAS DataBase Reference :61-76-7(CAS DataBase Reference)
EPA Substance Registry System :Phenylephrine hydrochloride (61-76-7)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.

Description

R-(-)-Phenylephrine is an adrenergic α1A receptor agonist (Ki = 1.4 μM) that demonstrates selectivity against the α1B and α1C receptor subtypes (Kis = 23.9 and 47.8 μM, respectively). By stimulating adrenergic α1 receptors, L-phenylephrine can induce aortic smooth muscle contractions, although reported relative affinity and potency values in rabbit are 5-fold weaker compared to that of L-norepinephrine . This compound is frequently used to precontract smooth muscle in preparations designed to study the properties of various vasodilator agents.

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