Medetomidine hydrochloride
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- Product name: Medetomidine hydrochloride
- CAS: 86347-15-1
- MF: C13H17ClN2
- MW: 236.74
- EINECS:645-306-0
- MDL Number:
- Synonyms:(r)-4-[1-(2,3-dimethylphenyl)ethyl]-1h-imidazole hydrochloride;1H-Imidazole, 5-[1-(2,3-dimethylphenyl)ethyl]-, hydrochloride (1:1);5-[1-(2,3-diMethylphenyl)ethyl]-1H-IMidazole hydrochloride;edetomidine;Medetomidine hydrochloride (R)-4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride;5-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole monohydrochloride;Metetomidine HCl;(R)-4-[1-(2
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Properties
Melting point :164-166°C
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :Acetonitrile (Slightly), Methanol (Slightly), Water (Slightly)
form :Solid
color :White to Off-White
InChI :InChI=1S/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H
InChIKey :VPNGEIHDPSLNMU-UHFFFAOYSA-N
SMILES :C(C1N=CNC=1)(C1C=CC=C(C)C=1C)C.Cl
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :Acetonitrile (Slightly), Methanol (Slightly), Water (Slightly)
form :Solid
color :White to Off-White
InChI :InChI=1S/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H
InChIKey :VPNGEIHDPSLNMU-UHFFFAOYSA-N
SMILES :C(C1N=CNC=1)(C1C=CC=C(C)C=1C)C.Cl
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Medetomidine is an imidazole derivative that acts as a selective agonist of α2-adrenoceptors (Ki = 1.08 nM vs. 1750 nM for α1-adrenoceptors). Medetomidine is a mixture of D and L isomers, with the D form, known as dexmedetomidine , described as the active form. Through its effect on α2-adrenoceptors, medetomidine has sedative, antinociceptive, analgesic, and hypothermic actions. Its effects on pain are additive or synergistic with fentanyl-type opioids. The effects of medetomidine are effectively countered by α2-adrenoceptor antagonists, like atipamezole. Selective α2-adrenoceptor agonists, including medetomidine, have anesthetic sparing properties, greatly reducing the dose of anesthetic required following premedication with the α2-adrenoceptor agonist.Related product price
- Ethylparaben
₹1953-49600.15 - Triprolidine hydrochloride
₹4330-16995.25 - 145108-58-3
₹4100-46515.03
Suppliers and manufacturers
ALS INDIA LIFE SCIENCES
A.J Chemicals
Pharmaffiliates Analytics and Synthetics P. Ltd
SynZeal Research Pvt Ltd
TCI Chemicals (India) Pvt. Ltd.
