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Medetomidine hydrochloride

Medetomidine hydrochloride Structure
CAS No.
86347-15-1
Chemical Name:
Medetomidine hydrochloride
Synonyms
MEDETOMIDINE HYDROCHLORIDE;edetomidine;(R)-4-[1-(2;medeomidine hcl;Metetomidine HCl;Ethyl Acetate Impurity 85;Medetomidine HCl (MPV-785);Metoclopramide (metoclopramide);Medetomidine Hydrochloride Impurities;Medetomidine (hydrochloride) cas86347-15-1
CBNumber:
CB52130917
Molecular Formula:
C13H17ClN2
Molecular Weight:
236.74
MOL File:
86347-15-1.mol
Modify Date:
2024/6/19 22:55:17

Medetomidine hydrochloride Properties

Melting point 164-166°C
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility Acetonitrile (Slightly), Methanol (Slightly), Water (Slightly)
form Solid
color White to Off-White
InChI InChI=1S/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H
InChIKey VPNGEIHDPSLNMU-UHFFFAOYSA-N
SMILES C(C1N=CNC=1)(C1C=CC=C(C)C=1C)C.Cl

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H317-H319
Precautionary statements  P280-P305+P351+P338

Medetomidine hydrochloride Chemical Properties,Uses,Production

Description

Medetomidine hydrochloride is a potent, highly selective α2-adrenoceptor agonist (Ki values are 1.08 and 1750 nM for α2- and α1-adrenoceptors respectively). It is an imidazole compound. Medetomidine hydrochloride shows greater selectivity over α1-adrenoceptors than clonidine and UK 14,304 (1620-, 220- and 300-fold respectively). In addition, it influences the adrenergic system by mimicking the action of adrenergic neurotransmitters.

Chemical Properties

White Solid

Side effects

Medetomidine hydrochloride is an alpha-2 adrenoreceptor agonist. Symptoms after absorption may involve clinical effects, including dose dependent sedation, respiratory depression, bradycardia, hypotension, a dry mouth, and hyperglycaemia. Ventricular arrhythmias have also been reported. Respiratory and haemodynamic symptoms should be treated symptomatically.

Medetomidine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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(r)-4-[1-(2,3-dimethylphenyl)ethyl]-1h-imidazole hydrochloride 1H-Imidazole, 5-[1-(2,3-dimethylphenyl)ethyl]-, hydrochloride (1:1) 5-[1-(2,3-diMethylphenyl)ethyl]-1H-IMidazole hydrochloride edetomidine Medetomidine hydrochloride (R)-4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride 5-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole monohydrochloride Metetomidine HCl (R)-4-[1-(2 3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride Medetomidine (hydrochloride) cas86347-15-1 SIMS1031 Medetomidine HCl ---86347-15-1 25g 2-amino-5-(2-ethoxyanilino)-4-hydroxy-1H-pyrimidin-6-one Medetomidine Hcl Medetomidine Hydrochloride (R)-4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride USP/EP/BP Medetomidine Hydrochloride Impurities Metoclopramide (metoclopramide) medeomidine hcl Medetomidine HCl (MPV-785) MEDETOMIDINE HYDROCHLORIDE Medetomidine hydrochloride,anxiolysis,inhibit,sedation,Medetomidine,α2-adrenoceptor,MPV-785,peripheral nervous system,analgesia,MPV 785,central nervous system,Inhibitor,muscle relaxation,Beta Receptor,Adrenergic Receptor Ethyl Acetate Impurity 85 86347-15-1 Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Inhibitors