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ChemicalBook > Product Catalogue >API >Antibiotics >Other antibiotic Drugs >Leptomycin B

Leptomycin B

Leptomycin B Structure
  • ₹6440.88 - ₹40431.38
  • Product name: Leptomycin B
  • CAS: 87081-35-4
  • MF: C33H48O6
  • MW: 540.73
  • EINECS:617-954-4
  • MDL Number:MFCD06795848
  • Synonyms:(2E,10Z,12E,16Z,18E)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-19-(3-methyl-6-oxo-2,3-dihydropyran-2-yl)-8-oxo-nonadeca-2,10,12,16,18-pentaenoic acid;2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-;2,10,12,16,18-Nonadecapentanoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-;(2E,5S,6R,7S,9R,10E,12E,15R,16Z,18E)-19-[(2S,3S)-3,6-Dihydro-3-methyl-6-oxo-2H-pyran-2-yl]-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-2,10,12,16,18-nonadecapentaenoicacid;LeptoMycin B( CI 940, LMB);antibioticcl1957a ;CI-940, Elactocin, PD 114720, ATS 1287B, Mantuamycin, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-2,10,12,16,18-Nonadecapentaenoic acid;Elactocin, ATS 1287B, CI 940, CL 1957A, PD 114720, MantuaMycin
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5μG
  • 0.5μG
  • ManufacturerSigma-Aldrich(India)
  • Product numberL2913
  • Product descriptionLeptomycin B solution from Streptomyces sp. ≥95% (HPLC), Supplied in methanol: water (7:3)
  • Packaging0.5μG
  • Price₹6440.88
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberL2913
  • Product descriptionLeptomycin B solution from Streptomyces sp. ≥95% (HPLC), Supplied in methanol: water (7:3)
  • Packaging5μG
  • Price₹40431.38
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) L2913 Leptomycin B solution from Streptomyces sp. ≥95% (HPLC), Supplied in methanol: water (7:3) 0.5μG ₹6440.88 2022-06-14 Buy
Sigma-Aldrich(India) L2913 Leptomycin B solution from Streptomyces sp. ≥95% (HPLC), Supplied in methanol: water (7:3) 5μG ₹40431.38 2022-06-14 Buy

Properties

Melting point :41-44°, with prior softening (Hokanson)
alpha :D -24.5° (c = 0.70 in MeOH); D23 -157 ° (c = 0.7% in chloroform)
Boiling point :725.8±60.0 °C(Predicted)
Density :1.072±0.06 g/cm3(Predicted)
Flash point :11°(52°F)
storage temp. :−20°C
solubility :Supplied in solution in ethanol (1 mg/ml). Further dilutions may be made with either ethanol or DMSO.
form :Liquid
pka :5.10±0.33(Predicted)
color :White to off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions or dilutions in DMSO are not stable. Solutions should be made fresh and used within one working day.

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P307+P311, P321,P405, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Potent, specific inhibitor of nuclear export signal (NES)-dependent protein export from the nucleus

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