Welcome to chemicalbook!
China english Japan Germany India
400-158-6606
18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
Structured search
Inquriy
Try our best to find the right business for you.
Messages
Do not miss inquiry messages Please log in to view all inquiry messages.
head sculpture My chemicalbook

Welcome back!

RFQ
skype
MY Account
Top
ChemicalBook > Product Catalogue >Natural Products >Alkaloids >9-Aminocamptothecin

9-Aminocamptothecin

9-Aminocamptothecin Structure
  • ₹32700
  • Product name: 9-Aminocamptothecin
  • CAS: 91421-43-1
  • MF: C20H17N3O4
  • MW: 363.37
  • EINECS:
  • MDL Number:MFCD00909855
  • Synonyms:4':6,7)indolizino(1,2-B)quinoline-3,14(4H,12H)-dione;4':6,7)indolizino(1,2-B)quinoline-3,14(4H,12H)-dione, 10-amino-4-ethyl-4-hydroxy-, (S)-;CAMPTOTHECIN, 9-AMINO-(RG);(S)-10-AMino-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;(S)-10-Amino-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]-indolizino[1,2-b]quinoline-3,14(4H,12H)-di;CAMPTOTHECIN, 9-AMINO-;AMinocaMptothecin;9-AMINO-CAMPTOTHECIN
Price1 Properties Safety Information Description
1 prices
Selected condition：

Brand

  • TCI Chemicals (India)

Package

  • 10MG
  • ManufacturerTCI Chemicals (India)
  • Product numberA2063
  • Product description9-Aminocamptothecin
  • Packaging10MG
  • Price₹32700
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) A2063 9-Aminocamptothecin 10MG ₹32700 2022-05-26 Buy

Properties

Melting point :142.0-145.0 °C
Boiling point :819.6±65.0 °C(Predicted)
Density :1.55±0.1 g/cm3(Predicted)
storage temp. :2-8°C(protect from light)
solubility :≤1mg/ml in DMSO;1mg/ml in dimethyl formamide
form :powder to crystal
pka :11.23±0.20(Predicted)
color :Light yellow to Yellow to Orange
Merck :14,431
InChIKey :FUXVKZWTXQUGMW-FQEVSTJZSA-N
CAS DataBase Reference :91421-43-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

DNA topoisomerases relax supercoiled DNA during replication, transcription, recombination, repair, and chromosome condensation. The relaxation of DNA supercoiling by topoisomerase I at single-strand breaks represents a target for anticancer agents to intercalate between DNA base pairs, leading to the activation of apoptotic and cell cycle arrest pathways. 9-amino Camptothecin is a topoisomerase I inhibitor that was developed as a more water-soluble analog of camptothecin . It is cytotoxic to HT-29 cells at an IC50 value of 19 nM, induces DNA damage in whole cells at a concentration of 85 nM, and demonstrates significant anti-tumor activity in clinical studies.

More related product prices

(+)-Camptothecin Betaine Glycine 10-Hydroxycamptothecin SN-38-D3 Rubitecan 9-Aminocamptothecin

Related product price

Suppliers and manufacturers

career henan chemical co
9-Aminocamptothecin
₹1.00 /1KG
9-Aminocamptothecin CAS:91421-43-1
CLEARSYNTH LABS LTD. TCI Chemicals (India) Pvt. Ltd. Pharmaffiliates Analytics and Synthetics P. Ltd Clearsynth Labs Pharma Affiliates
Chengdu GLP biotechnology Co Ltd
BOC Sciences
Chongqing Chemdad Co., Ltd
CONIER CHEM AND PHARMA LIMITED