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ChemicalBook > Product Catalogue >API >Synthetic Anti-infective Drugs >Antiviral drugs >Arbidol hydrochloride

Arbidol hydrochloride

Arbidol hydrochloride Structure
  • ₹7144.5 - ₹28956.88
  • Product name: Arbidol hydrochloride
  • CAS: 131707-23-8
  • MF: C22H26BrClN2O3S
  • MW: 513.88
  • EINECS:680-680-9
  • MDL Number:MFCD00344795
  • Synonyms:1H-INDOLE-3-CARBOXYLIC ACID, 6-BROMO-4-[(DIMETHYLAMINO)METHYL]-5-HYDROXY-1-METHYL-2-[(PHENYLTHIO)METHYL]-, ETHYL ESTER, MONOHYDROCHLORIDE;6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylthio)methyl]-1h-indole-3-carboxylic acid ethyl ester monohydrochloride;ARBIDOL HCL;ARBIDOL HYDROCHLORIDE;Arbidol hydrochloride hydrate;ARBIDOLHYDROCHLORIDE(FORR&DONLY);HYDROCHLORIDEOFETHYL6-BROMO-4-((DIMETHYLAMINO)METHYL)-5.;1h-indole-3-carboxylic acid, 6-bromo-4-((dimethylamino)methyl)-5-hydroxy-1-methyl-2-((phenylthio)methyl)-, ethyl ester, monohydrochloride, hydrate
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0860
  • Product descriptionArbidol hydrochloride ≥98% (HPLC)
  • Packaging10MG
  • Price₹7144.5
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0860
  • Product descriptionArbidol hydrochloride ≥98% (HPLC)
  • Packaging50MG
  • Price₹28956.88
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML0860 Arbidol hydrochloride ≥98% (HPLC) 10MG ₹7144.5 2022-06-14 Buy
Sigma-Aldrich(India) SML0860 Arbidol hydrochloride ≥98% (HPLC) 50MG ₹28956.88 2022-06-14 Buy

Properties

Melting point :133-137?C
storage temp. :-20°C
solubility :DMSO: soluble20mg/mL protein, clear
form :powder
color :white to beige
Stability :Hygroscopic
InChI :InChI=1S/C22H25BrN2O3S.ClH/c1-5-28-22(27)20-18(13-29-14-9-7-6-8-10-14)25(4)17-11-16(23)21(26)15(19(17)20)12-24(2)3;/h6-11,26H,5,12-13H2,1-4H3;1H
InChIKey :OMZHXQXQJGCSKN-UHFFFAOYSA-N
SMILES :C(C1=C(N(C)C2=CC(Br)=C(O)C(CN(C)C)=C12)CSC1C=CC=CC=1)(=O)OCC.Cl
CAS DataBase Reference :131707-23-8(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

Arbidol is a broad-spectrum, indole-based antiviral compound that blocks viral fusion with target membranes, prohibiting viral entry into cells. Because arbidol targets a common critical step for viral replication, it is effective against numerous viruses, including influenza A, B, and C and hepatitis B and C (IC50s range from 3-12.5 μg/ml). Besides its antiviral action, arbidol has been reported to produce an immunomodulatory response by inducing interferon production and stimulating the phagocytic function of macrophages.

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