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BROMOENOL LACTONE

BROMOENOL LACTONE Structure
  • ₹21650
  • Product name: BROMOENOL LACTONE
  • CAS: 88070-98-8
  • MF: C16H13BrO2
  • MW: 317.18
  • EINECS:
  • MDL Number:MFCD00270871
  • Synonyms:E-6-(BROMOETHYLENE)TETRAHYDRO-3-(1-NAPHTHYL)-2H-PYRAN-2-ONE;(E)-6-(BROMOMETHYLENE)TETRAHYDRO-3-(1-NAPHTHALENYL)-2H-PYRAN-2-ONE;(E)-6-(BROMOMETHYLENE)TETRAHYDRO-3-(1-NAPTHALENYL)-2H-PYRAN-2-ONE;HELSS;HALOENOL LACTONE;HALOENOL LACTONE SUICIDE SUBSTRATE;BEL;BROMOENOL LACTONE
Price1 Properties Safety Information Description
1 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberB1552
  • Product descriptionBromoenol lactone ≥98% (TLC)
  • Packaging5MG
  • Price₹21650
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) B1552 Bromoenol lactone ≥98% (TLC) 5MG ₹21650 2022-06-14 Buy

Properties

Melting point :103-106℃
Boiling point :467.0±45.0 °C(Predicted)
Density :1.538±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: Dilute in aqueous medium immediately prior to use and store on ice for no more than 12 hours.soluble
form :White solid.
color :White to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

BEL is a selective, potent, irreversible, mechanism-based inhibitor of myocardial cytosolic calcium-independent phospholipase A2 (iPLA2) with a Ki value of 180 nM. BEL also inhibits macrophage iPLA2 in a concentration-dependent manner with an IC50 value of 60 nM and is an effective enzyme-activated irreversible inhibitor of chymotrypsin (Ki = 636 nM).

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