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U-73343

U-73343 Structure
  • ₹15469.99 - ₹23501.08
  • Product name: U-73343
  • CAS: 142878-12-4
  • MF: C29H42N2O3
  • MW: 466.66
  • EINECS:
  • MDL Number:MFCD00211221
  • Synonyms:U-73343;1-[6-[((17Β)-3-METHOXYESTRA-1,3,5[10]-TRIEN-17-YL)AMINO]HEXYL]-2,5-PYRROLIDINEDIONE;1-[6-((17BETA-3-METHOXYESTRA-1,3,5(10)-TRIEN-17-YL)AMINO)HEXYL]-2,5-PYRROLIDINEDIONE;U-73343;1-[6-[((17β)-3-methoxyestra-1,3,5[10]-trien-17-yl)amino]hexyl]-2,5-pyrrolidinedione;3-Methoxy-17-[6-(2,5-dioxopyrrolidin-1-yl)hexylamino]estra-1,3,5(10)-triene;U73343, U-73343, U 73343;U-73343 - CAS 142878-12-4 - Calbiochem;2,5-Pyrrolidinedione, 1-[6-[[(17β)-3-methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-
Price3 Properties Safety Information Description
3 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 1MG
  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product number662041
  • Product descriptionU-73343 - CAS 142878-12-4 - Calbiochem A cell-permeable analog of U-73122 that acts as a very weak inhibitor of phospholipase C. Suitable as a negative control.
  • Packaging5MG
  • Price₹15469.99
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberU6881
  • Product descriptionU-73343
  • Packaging1MG
  • Price₹16345.75
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberU6881
  • Product descriptionU-73343
  • Packaging5MG
  • Price₹23501.08
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 662041 U-73343 - CAS 142878-12-4 - Calbiochem A cell-permeable analog of U-73122 that acts as a very weak inhibitor of phospholipase C. Suitable as a negative control. 5MG ₹15469.99 2022-06-14 Buy
Sigma-Aldrich(India) U6881 U-73343 1MG ₹16345.75 2022-06-14 Buy
Sigma-Aldrich(India) U6881 U-73343 5MG ₹23501.08 2022-06-14 Buy

Properties

Boiling point :641.5±55.0 °C(Predicted)
Density :1.15±0.1 g/cm3(Predicted)
storage temp. :+15C to +30C
solubility :ethanol: 0.93 mg/mL
form :powder
pka :10.68±0.40(Predicted)
color :white
Stability :Stable for 1 year from date of purchase as supplied. Dried films prepared from chloroform solution are stable for at least 1 month at -20°. It is preferable to dissolve U-73343 immediately before use if at all possible. Use caution and retest potency if attempting.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

U-73122 is an inhibitor of PLC-dependent processes, however, the mechanism of action remains unclear. The IC50 values for inhibition of platelet aggregation induced by collagen or thrombin are 0.6 and 5 μM, respectively. It also exhibits inhibitory activity against HIV-1 integrase with an IC50 value of 7 μM. U-73343 is a close structural analog of U-73122 that does not inhibit PLC, making it useful as a negative control for PLC inhibition.

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