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ChemicalBook > Product Catalogue >Biochemical Engineering >Biological response modifiers >Bestatin

Bestatin

Bestatin Structure
  • ₹9300 - ₹1611522.08
  • Product name: Bestatin
  • CAS: 58970-76-6
  • MF: C16H24N2O4
  • MW: 308.37
  • EINECS:261-529-2
  • MDL Number:MFCD00083262
  • Synonyms:UbenaMix, Inobestin, NK 421;L-Leucine,N-[(2S,3R)-3-aMino-2-hydroxy-1-oxo-4-phenylbutyl]-;N-[(2S,3R)-3-AMino-2-hydroxy-4-phenylbutyryl]-L-leucine 97%;3-(r)-amino-2-(s)-hydroxy-4-phenylbutanoyl-(s)-leucine ;n-(3-amino-2-hydroxy-1-oxo-4-phenylbutyl)-,(s-(r*,s*))-l-leucin ;nk421 ;N-[(2S,3R)-3-AMINO-2-HYDROXY-1-OXO-4-PHENYLBUTYL]-L-LEUCINE;N-((2S,3R)-3-AMINO-2-HYDROXY-4-PHENYLBUTYRYL)-L-LEUCINE
13 prices
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Brand

  • Sigma-Aldrich
  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 500MG
  • 200484-250MG
  • 250MG
  • 1G
  • 200484-500MG
  • 200484-10MG
  • 200484-200MG
  • 200484-1GM
  • ManufacturerSigma-Aldrich
  • Product number200484-M
  • Product descriptionBestatin - CAS 58970-76-6 - Calbiochem Binds to cell surfaces and inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase.
  • Packaging200484-10MG
  • Price₹16670.01
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number200484-M
  • Product descriptionBestatin - CAS 58970-76-6 - Calbiochem Binds to cell surfaces and inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase.
  • Packaging200484-500MG
  • Price₹883597.12
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number200484-M
  • Product descriptionBestatin - CAS 58970-76-6 - Calbiochem Binds to cell surfaces and inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase.
  • Packaging200484-1GM
  • Price₹1611522.08
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number200484-M
  • Product descriptionBestatin - CAS 58970-76-6 - Calbiochem Binds to cell surfaces and inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase.
  • Packaging200484-200MG
  • Price₹1611522.08
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number200484-M
  • Product descriptionBestatin - CAS 58970-76-6 - Calbiochem Binds to cell surfaces and inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase.
  • Packaging200484-250MG
  • Price₹1611522.08
  • Updated2022-06-14
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberU0111
  • Product descriptionUbenimex
  • Packaging250MG
  • Price₹9300
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberU0111
  • Product descriptionUbenimex
  • Packaging1G
  • Price₹22000
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number200484-M
  • Product descriptionBestatin - CAS 58970-76-6 - Calbiochem Binds to cell surfaces and inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase.
  • Packaging200484-10MG
  • Price₹16670.01
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number482609
  • Product descriptionN-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine 97%
  • Packaging500MG
  • Price₹19723.15
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number200484-M
  • Product descriptionBestatin - CAS 58970-76-6 - Calbiochem Binds to cell surfaces and inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase.
  • Packaging200484-500MG
  • Price₹883597.12
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number200484-M
  • Product descriptionBestatin - CAS 58970-76-6 - Calbiochem Binds to cell surfaces and inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase.
  • Packaging200484-1GM
  • Price₹1611522.08
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number200484-M
  • Product descriptionBestatin - CAS 58970-76-6 - Calbiochem Binds to cell surfaces and inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase.
  • Packaging200484-200MG
  • Price₹1611522.08
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number200484-M
  • Product descriptionBestatin - CAS 58970-76-6 - Calbiochem Binds to cell surfaces and inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase.
  • Packaging200484-250MG
  • Price₹1611522.08
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich 200484-M Bestatin - CAS 58970-76-6 - Calbiochem Binds to cell surfaces and inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase. 200484-10MG ₹16670.01 2022-06-14 Buy
Sigma-Aldrich 200484-M Bestatin - CAS 58970-76-6 - Calbiochem Binds to cell surfaces and inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase. 200484-500MG ₹883597.12 2022-06-14 Buy
Sigma-Aldrich 200484-M Bestatin - CAS 58970-76-6 - Calbiochem Binds to cell surfaces and inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase. 200484-1GM ₹1611522.08 2022-06-14 Buy
Sigma-Aldrich 200484-M Bestatin - CAS 58970-76-6 - Calbiochem Binds to cell surfaces and inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase. 200484-200MG ₹1611522.08 2022-06-14 Buy
Sigma-Aldrich 200484-M Bestatin - CAS 58970-76-6 - Calbiochem Binds to cell surfaces and inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase. 200484-250MG ₹1611522.08 2022-06-14 Buy
TCI Chemicals (India) U0111 Ubenimex 250MG ₹9300 2022-05-26 Buy
TCI Chemicals (India) U0111 Ubenimex 1G ₹22000 2022-05-26 Buy
Sigma-Aldrich(India) 200484-M Bestatin - CAS 58970-76-6 - Calbiochem Binds to cell surfaces and inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase. 200484-10MG ₹16670.01 2022-06-14 Buy
Sigma-Aldrich(India) 482609 N-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine 97% 500MG ₹19723.15 2022-06-14 Buy
Sigma-Aldrich(India) 200484-M Bestatin - CAS 58970-76-6 - Calbiochem Binds to cell surfaces and inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase. 200484-500MG ₹883597.12 2022-06-14 Buy
Sigma-Aldrich(India) 200484-M Bestatin - CAS 58970-76-6 - Calbiochem Binds to cell surfaces and inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase. 200484-1GM ₹1611522.08 2022-06-14 Buy
Sigma-Aldrich(India) 200484-M Bestatin - CAS 58970-76-6 - Calbiochem Binds to cell surfaces and inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase. 200484-200MG ₹1611522.08 2022-06-14 Buy
Sigma-Aldrich(India) 200484-M Bestatin - CAS 58970-76-6 - Calbiochem Binds to cell surfaces and inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase. 200484-250MG ₹1611522.08 2022-06-14 Buy

Properties

Melting point :245 °C (dec.)(lit.)
alpha :D20 -15.5° (c = 1.0 in 1N HCl)
Boiling point :448.76°C (rough estimate)
Density :1.0917 (rough estimate)
refractive index :1.5800 (estimate)
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :Aqueous Acid (Slightly, Sonicated), DMSO (Slightly, Heated)
pka :8.1, 3.1(at 25℃)
form :Powder
color :White
optical activity :[α]20/D 11°, c = 1 in 1 M NaOH
Water Solubility :Soluble in water (<1 25), DMSO (2 mg/ml), methanol (5 mg/ml), 1eq. NaOH (50 mM), ethanol (<1 mg/ml at 25°C), acetic acid, aq. HCl, and alkaline solution. Insoluble in ethyl acetate, benzene, hexane, and chloroform.
Merck :13,9910
InChIKey :VGGGPCQERPFHOB-RDBSUJKOSA-N
CAS DataBase Reference :58970-76-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.

Description

Bestatin can indirectly act on monocytes by inhibiting Aminopeptidase B, which in turn inhibits the catabolism of tuftsin. Bestatin has also been shown to inhibit Leukotriene A4?hydrolase. It can directly stimulate lymphocytes through its fixation on the cell surface. The agent has been used in multiple leukemia studies. Bestatin is an aminopeptidase inhibitor, inhibits enkephalin metabolism and leukotriene A4 hydrolase. Inhibits tumor cell proliferation.

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