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ChemicalBook > Product Catalogue >Biochemical Engineering >Chinese Herbs >Betulinic acid

Betulinic acid

Betulinic acid  Structure
  • ₹4968.68 - ₹48500
  • Product name: Betulinic acid
  • CAS: 472-15-1
  • MF: C30H48O3
  • MW: 456.71
  • EINECS:207-448-8
  • MDL Number:MFCD00009619
  • Synonyms:3BETA-HYDROXY-20(29)-LUPENE-28-OIC ACID;3BETA-HYDROXY-20(29)-LUPAENE-28-OIC ACID;3B-HYDROXY-20(29)-LUPENE-28-OIC ACID;Birch bark extract/β-Amyrin/betulinic acid;3-B-HYDROXY-LUPA-20(30)-ENE 28-OIC ACID;BETULINIC ACID;LUP-20(29)-EN-28-OIC ACID, 3-HYDROXY-, (3B)-;Lup-20(29)-en-28-oic acid, 3-hydroxy-, (3beta)-
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 5MG
  • 10MG
  • 25MG
  • 100MG
  • 500MG
  • 1G
  • ManufacturerTCI Chemicals (India)
  • Product numberB2836
  • Product descriptionBetulinic Acid min. 97.0 %
  • Packaging100MG
  • Price₹10600
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberB2836
  • Product descriptionBetulinic Acid min. 97.0 %
  • Packaging1G
  • Price₹48500
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberB8936
  • Product descriptionBetulinic acid ≥98% (HPLC)
  • Packaging5MG
  • Price₹4968.68
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number91466
  • Product descriptionBetulinic acid analytical standard
  • Packaging10MG
  • Price₹9601.78
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number855057
  • Product descriptionBetulinic acid technical grade, 90%
  • Packaging100MG
  • Price₹11474.5
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberB8936
  • Product descriptionBetulinic acid ≥98% (HPLC)
  • Packaging25MG
  • Price₹16508.13
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number855057
  • Product descriptionBetulinic acid technical grade, 90%
  • Packaging500MG
  • Price₹29909.48
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) B2836 Betulinic Acid min. 97.0 % 100MG ₹10600 2022-05-26 Buy
TCI Chemicals (India) B2836 Betulinic Acid min. 97.0 % 1G ₹48500 2022-05-26 Buy
Sigma-Aldrich(India) B8936 Betulinic acid ≥98% (HPLC) 5MG ₹4968.68 2022-06-14 Buy
Sigma-Aldrich(India) 91466 Betulinic acid analytical standard 10MG ₹9601.78 2022-06-14 Buy
Sigma-Aldrich(India) 855057 Betulinic acid technical grade, 90% 100MG ₹11474.5 2022-06-14 Buy
Sigma-Aldrich(India) B8936 Betulinic acid ≥98% (HPLC) 25MG ₹16508.13 2022-06-14 Buy
Sigma-Aldrich(India) 855057 Betulinic acid technical grade, 90% 500MG ₹29909.48 2022-06-14 Buy

Properties

Melting point :295-298 °C (dec.) (lit.)
Boiling point :550.0±33.0 °C(Predicted)
alpha :D25 +7.5° (c = 0.37 in pyridine)
Density :1.065±0.06 g/cm3(Predicted)
refractive index :7.8 ° (C=0.9, Pyridine)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
form :Solid
pka :4.61±0.70(Predicted)
color :White or off-white
optical activity :[α]20/D +7.8°, c = 0.9 in pyridine
Merck :14,1190
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
InChIKey :QGJZLNKBHJESQX-FZFNOLFKSA-N
LogP :7.653 (est)
CAS DataBase Reference :472-15-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P273 Avoid release to the environment.

Description

Betulinic acid is a natural plant triterpenoid that is structurally related to mammalian bile acids. It is an agonist of the G protein-coupled bile acid receptor TGR5 (EC50 = 1 μM), which might be linked with its ability to alter gene expression and fatty liver development in cells and mice given ethanol. Betulinic acid also reduces NF-κB signaling and expression of microRNA-33 in LPS-treated macrophages, increasing levels of the ATP-binding cassette (ABC) cholesterol transporter ABCA1. It also inhibits replication of HIV-1 (IC50 = 1.4 μM) and has cytotoxic effects against cancer cells.

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