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Bupropion

Bupropion Structure
  • ₹0
  • Product name: Bupropion
  • CAS: 34911-55-2
  • MF: C13H18ClNO
  • MW: 239.74
  • EINECS:
  • MDL Number:MFCD00055209
  • Synonyms:m-chloro-a-(tert-butylamino)propiophenone;Bupropion;BUPROPION/AMFEBUTAMONE;Wellbatrin:Wellbutrin;rac-(R*)-1-(3-Chlorophenyl)-2-(tert-butylamino)-1-propanone;Buproprion thioMorpholine carboxylic acid;Bupropion controlled release;1-Propanone,1-(3-chlorophenyl)-2-[(1,1-diMethylethyl)aMino]-
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Properties

Melting point :233-234°C
Boiling point :bp.005 52°
Density :1.066±0.06 g/cm3(Predicted)
solubility :ethanol: 193 mg/mL solutions may be stored for several days at 4 °C.
form :solid
pka :pKa 7.0 (Uncertain)
color :white
BCS Class :1
CAS DataBase Reference :34911-55-2(CAS DataBase Reference)
EPA Substance Registry System :1-Propanone, 1-(3-chlorophenyl)-2-[(1,1-dimethylethyl)amino]- (34911-55-2)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Bupropion hydrochloride, an aminoketone structurally unrelated to tricyclics or tetracyclics, is a dopamine uptake blocker with antidepressant activity. Its clinical efficacy is reportedly comparable to that of amitriptyline, yet unlike most conventional antidepressants, bupropion hydrochloride is not associated with orthostatic hypotension or other cardiovascular side-effects.

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