CD437
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- ₹9380 - ₹81934.43
- Product name: CD437
- CAS: 125316-60-1
- MF: C27H26O3
- MW: 398.49
- EINECS:200-258-5
- MDL Number:MFCD03106506
- Synonyms:2-naphthalenecarboxylicacid,6-(4-hydroxy-3-tricyclo(3.3.1.1(3,7))dec-1-ylphen ;6-(4-hydroxy-3-tricyclo(3.3.1.1(3,7))dec-1-ylphenyl)-2-naphthalenecarboxylic ;AHPN, 6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid;O-DesMethyl Adapalene;CD 437/AHPN;Adapalene IMpurity F;Apoptosis Activator VI, CD437/AHPN ;ADAP-IME
3 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product number178496
- Product descriptionApoptosis Activator VI, CD437/AHPN - CAS 125316-60-1 - Calbiochem The Apoptosis Activator VI, CD437/AHPN, also referenced under CAS 125316-60-1, modulates Apoptosis. This small molecule/inhibitor is primarily used fo
- Packaging5MG
- Price₹9380
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberC5865
- Product descriptionCD437 ≥98% (HPLC), solid
- Packaging5MG
- Price₹20556.68
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberC5865
- Product descriptionCD437 ≥98% (HPLC), solid
- Packaging25MG
- Price₹81934.43
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 178496 | Apoptosis Activator VI, CD437/AHPN - CAS 125316-60-1 - Calbiochem The Apoptosis Activator VI, CD437/AHPN, also referenced under CAS 125316-60-1, modulates Apoptosis. This small molecule/inhibitor is primarily used fo | 5MG | ₹9380 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C5865 | CD437 ≥98% (HPLC), solid | 5MG | ₹20556.68 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C5865 | CD437 ≥98% (HPLC), solid | 25MG | ₹81934.43 | 2022-06-14 | Buy |
Properties
Melting point :271.6-276 °C
Boiling point :595.0±50.0 °C(Predicted)
Density :1.290
storage temp. :-20°C
solubility :DMSO: 26 mg/mL
form :solid
pka :4.17±0.30(Predicted)
color :yellow
Boiling point :595.0±50.0 °C(Predicted)
Density :1.290
storage temp. :-20°C
solubility :DMSO: 26 mg/mL
form :solid
pka :4.17±0.30(Predicted)
color :yellow
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
CD437 is the prototypical adamantyl arotinoid of the retinoid-related molecule family that acts as a selective agonist of retinoic acid receptor (RAR)γ (Kds = 6.5 μM, 2.5 μM, and 77 nM for RARα, β, and γ, respectively). CD437 is cytotoxic to the acute myeloid leukemia cell line NB4 (EC50 = 0.17 μM), inducing DNA damage by producing DNA double strand breaks. CD437 also induces cell cycle arrest and apoptosis in various other cancer cells including melanoma, breast, non-small lung, and prostate cancer cells through RAR-dependent and -independent signaling pathways.More related product prices
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₹4000-21790.73 - 106685-41-0
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