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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >GPCR & G Protein >Adenosine Receptor agonists >CGS 21680A

CGS 21680A

CGS 21680A Structure
  • ₹0
  • Product name: CGS 21680A
  • CAS: 124431-80-7
  • MF: C23H30ClN7O6
  • MW: 535.99
  • EINECS:
  • MDL Number:
  • Synonyms:CGS 21680 (HCl salt);CGS 21680A;4-[2-[[6-Amino-9-(N-ethyl-beta-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]benzenepropanoic acid monohydrochloride;Benzenepropanoic acid, 4-[2-[[6-amino-9-(N-ethyl-b-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]- hydrochloride (1:1);[3H]-CGS 21680A;CGS 21680A;CGS 21680 HCL;CGS 21680 HCl NEW;100688
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :204-206°C
storage temp. :Inert atmosphere,2-8°C
solubility :DMSO (Slightly, Heated), Methanol (Slightly, Heated)
form :Solid
color :White to Light Beige
Stability :Hygroscopic
CAS DataBase Reference :124431-80-7

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

CGS 21680 is a potent, selective agonist of the adenosine A2A receptor (Ki = 11-46 nM). It is less effective at adenosine A1 and A3 receptors (Kis = 0.5-3.1 and 0.6-1 μM, respectively) and is without effect at adenosine A2B (Ki > 10 μM). CGS 21680 is commonly used to study the actions of the adenosine A2A receptor in cells and tissues.

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