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ChemicalBook > Product Catalogue >API >Antibiotics >Cephalosporins Drugs >Cefixime

Cefixime

Cefixime Structure
  • ₹10760.05
  • Product name: Cefixime
  • CAS: 79350-37-1
  • MF: C16H15N5O7S2
  • MW: 453.45
  • EINECS:616-684-4
  • MDL Number:MFCD03788802
  • Synonyms:YTTERBIUM(III) IONOPHORE I;)(carboxymethoxy)imino)acetylamino)-3-ethenyl-8-oxo-,(6r-(6-alpha,7-beta(z))) ;cl284635 ;fk027 ;fr17027 ;8-[[2-(2-amino-1,3-thiazol-4-yl)-2-(carboxymethoxyimino)acetyl]amino]-4-ethenyl-7-oxo-2-thia-6-azabicyclo[4.2.0]oct-4-ene-5-carboxylic acid;(6R,7R)-7-[2-(2-AMINO-4-THIAZOLYL)GLOXYLAMIDO]-8-OXO-3-VINYL-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC ACID, 72-(Z)-[O-(CARBOXYMETHYL)OXIME]TRIHYDRATE;CEFIXME TRIHYDRATE
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Brand

  • Sigma-Aldrich(India)

Package

  • 100MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberCDS021590
  • Product descriptionCefixime
  • Packaging100MG
  • Price₹10760.05
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) CDS021590 Cefixime 100MG ₹10760.05 2022-06-14 Buy

Properties

Melting point :218-225°C
Density :1.85±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :Slightly soluble in water, soluble in methanol, sparingly soluble in anhydrous ethanol, practically insoluble in ethyl acetate.
pka :pKa 2.10 (Uncertain)
form :Solid
color :Off-White to Pale Yellow
Water Solubility :55.11 mg/L
BCS Class :4
Stability :Hygroscopic
CAS DataBase Reference :79350-37-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Cefixime is a third generation cephalosporin antibiotic. It is effective against a variety of Gram-negative bacteria, including E. coli, K. pneumoniae, and H. influenzae (MIC values range from <0.025 to 25 μg/ml). Cefixime binds penicillin-binding proteins and is stable to many penicillinases and β-lactamases. It is an effective, orally-active cephalosporin with applications in acute otitis media, respiratory tract infections, and urinary tract infections.

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