Cyclophosphamide
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- ₹0
- Product name: Cyclophosphamide
- CAS: 50-18-0
- MF: C7H15Cl2N2O2P
- MW: 261.09
- EINECS:200-015-4
- MDL Number:MFCD00005978
- Synonyms:2-(Bis(2-chloroethyl)amino)-2H-1,3,2-oxazaphosphorine 2-oxide;2H-1,3,2-Oxazaphosphorin-2-amine, N,N-bis(2-chloroethyl)tetrahydro-, 2-oxide;2-H-1,3,2-Oxazaphosphorinane;2H-1,3,2-Oxazaphosphosphorin-2-amine, N,N-bis(2-chloroethyl) tetrahydro-, 2-oxide;1-(Bis(2-chloroethyl)amino)-1-oxo-2-aza-5-oxaphosphoridine;2-(Di(2-chloroethyl)amino)-1-oxa-3-aza-2-phosphacyclohexane 2-oxide;Cyclophosphamide;2-Bis(2-chloroethyl)aminotetrahydro-2H-1,3,2-oxazophosphorine-2-oxide
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Properties
Melting point :41-45°C
Boiling point :336.1±52.0 °C(Predicted)
Density :1.33±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :≥11.85 mg/mL in H2O with gentle warming and ultrasonic; ≥13.05 mg/mL in DMSO; ≥50.8 mg/mL in EtOH
form :solid
pka :2.84±0.20(Predicted)
color :White to off-white
Water Solubility :Soluble. 1-5 g/100 mL at 23 ºC
BCS Class :1,3
Stability :Stable, but light sensitive. Incompatible with oxidizing agents.
CAS DataBase Reference :50-18-0(CAS DataBase Reference)
IARC :1 (Vol. 26, Sup 7, 100A) 2012
NIST Chemistry Reference :2-[Bis(2-chloroethylamino)]-tetrahydro-2h-1,3,2-oxazaphosphorine-2-oxide(50-18-0)
EPA Substance Registry System :Cyclophosphamide (50-18-0)
Boiling point :336.1±52.0 °C(Predicted)
Density :1.33±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :≥11.85 mg/mL in H2O with gentle warming and ultrasonic; ≥13.05 mg/mL in DMSO; ≥50.8 mg/mL in EtOH
form :solid
pka :2.84±0.20(Predicted)
color :White to off-white
Water Solubility :Soluble. 1-5 g/100 mL at 23 ºC
BCS Class :1,3
Stability :Stable, but light sensitive. Incompatible with oxidizing agents.
CAS DataBase Reference :50-18-0(CAS DataBase Reference)
IARC :1 (Vol. 26, Sup 7, 100A) 2012
NIST Chemistry Reference :2-[Bis(2-chloroethylamino)]-tetrahydro-2h-1,3,2-oxazaphosphorine-2-oxide(50-18-0)
EPA Substance Registry System :Cyclophosphamide (50-18-0)
Safety Information
Symbol(GHS): |
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Signal word: | Danger | |||||||||||||||||||||||||||||||||||
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Description
Cyclophosphamide USP is used to treat acute and chronic lymphocytic leukemia; lung cancer; rhabdomyosarcoma; neuroblastoma; ovarian and mammary carcinoma; multiple myeloma; lymphosarcoma; Burkitt’s lymphoma; Hodgkin’s disease; retinoblastoma; mycosis fungoidesRelated product price
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