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ChemicalBook > Product Catalogue >API >Anesthetic Agents >Skeletal muscle relaxants >DECAMETHONIUM BROMIDE

DECAMETHONIUM BROMIDE

DECAMETHONIUM BROMIDE Structure
  • ₹3800 - ₹43148.45
  • Product name: DECAMETHONIUM BROMIDE
  • CAS: 541-22-0
  • MF: C16H38Br2N2
  • MW: 418.29
  • EINECS:208-772-2
  • MDL Number:MFCD00011779
  • Synonyms:1,10-Decanediaminium,N,N,N,N’,N’,N’-hexamethyl-,dibromide ;10-decanediaminium,n,n,n,n’,n’,n’-hexamethyl-dibromide ;decacuran ;decamethoniumdibromide ;decamethylene-1,10-bistrimethylammoniumdibromide ;decamethylenebis(trimethyl-ammoniudibromide ;1,10-Decanediaminium, N1,N1,N1,N10,N10,N10-hexamethyl-, bromide (1:2);dekamethoniumbromid
Price5 Properties Safety Information Description
5 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 5G
  • 10G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberD1314
  • Product descriptionDecamethonium Bromide
  • Packaging5G
  • Price₹3800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberD1314
  • Product descriptionDecamethonium Bromide
  • Packaging25G
  • Price₹6900
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD1260
  • Product descriptionDecamethonium bromide crystalline
  • Packaging5G
  • Price₹10900.78
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD1260
  • Product descriptionDecamethonium bromide crystalline
  • Packaging10G
  • Price₹19604.08
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD1260
  • Product descriptionDecamethonium bromide crystalline
  • Packaging25G
  • Price₹43148.45
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) D1314 Decamethonium Bromide 5G ₹3800 2022-05-26 Buy
TCI Chemicals (India) D1314 Decamethonium Bromide 25G ₹6900 2022-05-26 Buy
Sigma-Aldrich(India) D1260 Decamethonium bromide crystalline 5G ₹10900.78 2022-06-14 Buy
Sigma-Aldrich(India) D1260 Decamethonium bromide crystalline 10G ₹19604.08 2022-06-14 Buy
Sigma-Aldrich(India) D1260 Decamethonium bromide crystalline 25G ₹43148.45 2022-06-14 Buy

Properties

Melting point :263-267 °C(lit.)
storage temp. :Inert atmosphere,Room Temperature
solubility :DMF: 2 mg/ml; DMSO: 16 mg/ml; Ethanol: 33 mg/ml; PBS (pH 7.2): 5 mg/ml
form :crystalline
color :off-white
Water Solubility :almost transparency
λmax :λ: 240 nm Amax: 0.04
λ: 250 nm Amax: 0.03
λ: 260 nm Amax: 0.02
λ: 500 nm Amax: 0.02 Merck :14,2847
BRN :3728288
Stability :Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference :541-22-0(CAS DataBase Reference)
EPA Substance Registry System :Decamethonium dibromide (541-22-0)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Decamethonium is a depolarizing neuromuscular blocking agent. It is a partial agonist of muscle-type nicotinic acetylcholine receptors (nAChRs). Decamethonium activates α1β1-containing adult mouse muscle-type nAChRs expressed in X. laevis oocytes with an EC50 value of 40 μM using voltage clamp electrophysiology. It is also a nondepolarizing antagonist of neuronal-type nAChRs, inhibiting mouse α7-, α3β2-, α3β4-, and α4β2-containing receptors with IC50 values of 7.4, 405, 28, and 59 μM, respectively. Decamethonoium is a competitive antagonist of α4β2-containing nAChRs expressed in SH-EP1 cells (IC50 = 52 μM for the human receptor). It also inhibits electric eel acetylcholinesterase (AChE) and blocks electrically-evoked tibialis muscle twitches in anesthetized cats with ED95 values of 35 and 70 μg/kg for cats under chloralose and ether anesthesia, respectively. Formulations containing decamethonium have been used to induce paralysis during anesthesia.

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Suppliers and manufacturers

career henan chemical co
DECAMETHONIUM BROMIDE
₹9.80 /1KG
DECAMETHONIUM BROMIDE CAS:541-22-0
Dideu Industries Group Limited
DECAMETHONIUM BROMIDE USP/EP/BP
₹1.10 /1g
DECAMETHONIUM BROMIDE USP/EP/BP CAS:541-22-0
TCI Chemicals (India) Pvt. Ltd. A.J Chemicals CLEARSYNTH LABS LTD.
Shaanxi Dideu Medichem Co. Ltd
TargetMol Chemicals Inc.
Dayang Chem (Hangzhou) Co.,Ltd.
InvivoChem
GIHI CHEMICALS CO.,LIMITED