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ChemicalBook > Product Catalogue >API >Circulatory system drugs >Angina Pectoris Drugs >Dipyridamole

Dipyridamole

Dipyridamole Structure
  • ₹4254.23 - ₹40301.48
  • Product name: Dipyridamole
  • CAS: 58-32-2
  • MF: C24H40N8O4
  • MW: 504.63
  • EINECS:200-374-7
  • MDL Number:MFCD00010555
  • Synonyms:2,2',2'',2'''-((4,8-Di(piperidin-1-yl)pyrimido[5,4-d]-pyrimidine-2,6-diyl)bis(azanetriyl))tetraet;Corosan;Coroxin;Curantyl;Dipyridamine;Dipyridan;Dipyudamine;Ethanol, 2,2',2'',2'''-(4,8-dipiperidinopyrimido(5,4-d)pyrimidine-2,6-diyldinitrilo)tetra-
Price6 Properties Safety Information Description
6 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 1G
  • 5G
  • 10G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberD2274
  • Product descriptionDipyridamole
  • Packaging5G
  • Price₹4800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberD2274
  • Product descriptionDipyridamole
  • Packaging25G
  • Price₹9300
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD9766
  • Product descriptionDipyridamole ≥98% (HPLC)
  • Packaging1G
  • Price₹4254.23
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD9766
  • Product descriptionDipyridamole ≥98% (HPLC)
  • Packaging5G
  • Price₹12654.43
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD9766
  • Product descriptionDipyridamole ≥98% (HPLC)
  • Packaging10G
  • Price₹20491.73
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD9766
  • Product descriptionDipyridamole ≥98% (HPLC)
  • Packaging25G
  • Price₹40301.48
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) D2274 Dipyridamole 5G ₹4800 2022-05-26 Buy
TCI Chemicals (India) D2274 Dipyridamole 25G ₹9300 2022-05-26 Buy
Sigma-Aldrich(India) D9766 Dipyridamole ≥98% (HPLC) 1G ₹4254.23 2022-06-14 Buy
Sigma-Aldrich(India) D9766 Dipyridamole ≥98% (HPLC) 5G ₹12654.43 2022-06-14 Buy
Sigma-Aldrich(India) D9766 Dipyridamole ≥98% (HPLC) 10G ₹20491.73 2022-06-14 Buy
Sigma-Aldrich(India) D9766 Dipyridamole ≥98% (HPLC) 25G ₹40301.48 2022-06-14 Buy

Properties

Melting point :165-166 °C (lit.)
Boiling point :593.96°C (rough estimate)
Density :1.2046 (rough estimate)
refractive index :1.6910 (estimate)
storage temp. :room temp
solubility :DMSO: soluble
form :powder
pka :pKa 6.4 (Uncertain)
color :yellow
Water Solubility :Soluble in chloroform, methanol, dilute acids, ethanol. Slightly soluble in water.
Merck :14,3346
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
NIST Chemistry Reference :Pyrimidine, 2,6-bis(diethanolamino)-4,8-dipiperidino-pyrimido-(5,4-d)-(58-32-2)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Dipyridamole is a phosphodiesterase (PDE)5A inhibitor (IC50 = 574 nM) that prevents platelet aggregation by increasing cGMP levels and blocking the reuptake of adenosine via red blood cells. It also scavenges the free radicals that inactivate cyclooxygenase, leading to the inhibition of platelet activation and thrombin generation. Dipyridamole has been used in combination with aspirin to prevent stroke and other cardiovascular events. Dipyridamole has also been shown to inhibit PDE11A with an IC50 value of 370 nM and equilibrative nucleoside transporter 1 with a Ki value of 8.18 nM.

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Suppliers and manufacturers

Glenmark Pharmaceuticals Limited Lakshmi Farmachem Solara Active Pharma Sciences Ltd Cohance Lifesciences (Previously RA Chem Pharma Ltd) Vijaya Pharma And Life Science Mylan Laboratories Ltd SETV ASRV LLP Unitrade Agencies Turakhia Brothers (Panchsheel Organics Limited) Opulent Pharma