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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Metabolism >Carbonic Anhydrase Inhibitors >Dorzolamide Hydrochloride

Dorzolamide Hydrochloride

Dorzolamide Hydrochloride Structure
  • ₹8800 - ₹27776.95
  • Product name: Dorzolamide Hydrochloride
  • CAS: 130693-82-2
  • MF: C10H17ClN2O4S3
  • MW: 360.9
  • EINECS:620-304-2
  • MDL Number:MFCD00884659
  • Synonyms:3-b)thiopyran-2-sulfonamide,5,6-dihydro-4-(ethylamino)-6-methyl-4h-thieno( ;mk-0507 ;monohydrochloride,(4s-trans)-7-dioxide ;Dorzolomide hydrochloride, >=99%;4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, hydrochloride;MK-507 (L-671152) HCl;4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, hydrochloride (1:1), (4S,6S)-;(4S,6S)-4-(Ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxid
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 200MG
  • 500MG
  • ManufacturerTCI Chemicals (India)
  • Product numberD4189
  • Product descriptionDorzolamide Hydrochloride
  • Packaging200MG
  • Price₹8800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1925
  • Product descriptionDorzolamide hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging500MG
  • Price₹27776.95
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) D4189 Dorzolamide Hydrochloride 200MG ₹8800 2022-05-26 Buy
Sigma-Aldrich(India) PHR1925 Dorzolamide hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material 500MG ₹27776.95 2022-06-14 Buy

Properties

Melting point :265-2670C
alpha :D24 -8.34° (c = 1 in methanol)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :Soluble in water, slightly soluble in methanol, very slightly soluble in anhydrous ethanol.
form :Solid
color :White to Off-White
λmax :254nm(CHCl3:MeOH= aq.)(lit.)
Merck :14,3426
BRN :5896026
CAS DataBase Reference :130693-82-2(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P314 Get medical advice/attention if you feel unwell.
P501 Dispose of contents/container to..…

Description

Dorzolamide is an inhibitor of carbonic anhydrase, inhibiting human isoforms II, V, VI, IX, XII, XIII, and XIV with Ki values between 3.5 and 52 nM. It less effectively inhibits human carbonic anhydrases I, III, and IV (Ki = 50, 8, and 8.5 μM, respectively). Topically applied inhibitors of carbonic anhydrase, including dorzolamide, are commonly used to treat glaucoma.

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Jigs Chemical ltd Siddhivinayakchemicals Flax Laboratories SHOBHA LIFE SCIENCES PRIVATE LIMITED KARPSCHEM LABORATORIES FDC Limited Hetero Drugs Limited Precise Biopharma Pvt Ltd Lake Chemicals Pvt Ltd Indoco Remedies Ltd