Duloxetine hydrochloride
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- ₹7674.93 - ₹31262.6
- Product name: Duloxetine hydrochloride
- CAS: 136434-34-9
- MF: C18H20ClNOS
- MW: 333.88
- EINECS:603-962-5
- MDL Number:MFCD06407958
- Synonyms:LY-248686 HCl;(γS)-N-methyl-γ-(1-naphthalenyloxy)-2-thiophenepropanamine, hydrochloride (1:1);(+)-N-Methyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine hydrochloride;LY-248686 hydrochloride;Duloxetine for system suitability;Duloxetine hydrochloride solution;(S)-N-Methyl-3-(1-naphthalenyloxy)-3-(2-thienyl) propanamine hydrochloride;Methanol（ Test Duloxetine HCl, 1.0 mg/mL as free base）
6 prices
Selected condition：
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 10MG
- 50MG
- 500MG
- 1G
- 1ML
- 5G
- ManufacturerTCI Chemicals (India)
- Product numberD4223
- Product descriptionDuloxetine Hydrochloride
- Packaging1G
- Price₹9100
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberD4223
- Product descriptionDuloxetine Hydrochloride
- Packaging5G
- Price₹18200
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML0474
- Product description(S)-Duloxetine hydrochloride ≥98% (HPLC)
- Packaging10MG
- Price₹7674.93
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberD-044
- Product descriptionDuloxetine hydrochloride solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant?
- Packaging1ML
- Price₹10041.5
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberPHR1865
- Product descriptionDuloxetine Hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging500MG
- Price₹22743.33
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML0474
- Product description(S)-Duloxetine hydrochloride ≥98% (HPLC)
- Packaging50MG
- Price₹31262.6
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | D4223 | Duloxetine Hydrochloride | 1G | ₹9100 | 2022-05-26 | Buy |
| TCI Chemicals (India) | D4223 | Duloxetine Hydrochloride | 5G | ₹18200 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | SML0474 | (S)-Duloxetine hydrochloride ≥98% (HPLC) | 10MG | ₹7674.93 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | D-044 | Duloxetine hydrochloride solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant? | 1ML | ₹10041.5 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR1865 | Duloxetine Hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material | 500MG | ₹22743.33 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML0474 | (S)-Duloxetine hydrochloride ≥98% (HPLC) | 50MG | ₹31262.6 | 2022-06-14 | Buy |
Properties
Melting point :118-122°C
Flash point :9℃
storage temp. :room temp
solubility :H2O: soluble5mg/mL (clear solution, warmed)
pka :pKa in DMF-water (66:34): 9.6(at 25℃)
form :powder
color :white to beige
optical activity :[α]/D +116 to +125°, c = 1 in methanol
Merck :14,3465
InChI :InChI=1/C18H19NOS.ClH/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16;/h2-10,13,17,19H,11-12H2,1H3;1H/t17-;/s3
InChIKey :BFFSMCNJSOPUAY-VOPAOICTNA-N
SMILES :C1(=CC=CS1)[C@H](CCNC)OC1=CC=CC2=CC=CC=C12.Cl |&1:5,r|
Flash point :9℃
storage temp. :room temp
solubility :H2O: soluble5mg/mL (clear solution, warmed)
pka :pKa in DMF-water (66:34): 9.6(at 25℃)
form :powder
color :white to beige
optical activity :[α]/D +116 to +125°, c = 1 in methanol
Merck :14,3465
InChI :InChI=1/C18H19NOS.ClH/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16;/h2-10,13,17,19H,11-12H2,1H3;1H/t17-;/s3
InChIKey :BFFSMCNJSOPUAY-VOPAOICTNA-N
SMILES :C1(=CC=CS1)[C@H](CCNC)OC1=CC=CC2=CC=CC=C12.Cl |&1:5,r|
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
(S)-Duloxetine is a potent inhibitor of serotonin and norepinephrine reuptake (Kis = 4.6 and 15.6 nM, respectively, for rat synaptosomes). It less effectively inhibits dopamine reuptake (Ki = 369 nM). It is effective in cells, tissues, and in vivo. (S)-Duloxetine has applications in many chronic medical conditions, including major depressive disorder, generalized anxiety disorder, chronic neuropathic and musculoskeletal pain, and fibromyalgia.More related product prices
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