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ChemicalBook > Product Catalogue >Biochemical Engineering >Chinese Herbs >(+)-FANGCHINOLINE

(+)-FANGCHINOLINE

(+)-FANGCHINOLINE Structure
  • ₹6600 - ₹13400
  • Product name: (+)-FANGCHINOLINE
  • CAS: 436-77-1
  • MF: C37H40N2O6
  • MW: 608.72
  • EINECS:
  • MDL Number:MFCD03427706
  • Synonyms:6,6',12-TRIMETHOXY-2,2'-DIMETHYLBERBAMAN-7-OL;(+)-FANGCHINOLINE;FANGCHINO-LINE;Fangchinoline, Demethyltetrandrine;Hanfangichin B;Berbaman-7-ol,6,6',12-trimethoxy-2,2'-dimethyl-, (1β)-;(1S)-6,6',12-Trimethoxy-2,2'-dimethylberbaman-7-ol;(1S)-7-Hydroxy-6,6',12-trimethoxy-2,2'-dimethylberbaman
2 prices
Selected condition:

Brand

  • TCI Chemicals (India)

Package

  • 20MG
  • 100MG
  • ManufacturerTCI Chemicals (India)
  • Product numberF1173
  • Product descriptionFangchinoline
  • Packaging20MG
  • Price₹6600
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberF1173
  • Product descriptionFangchinoline
  • Packaging100MG
  • Price₹13400
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) F1173 Fangchinoline 20MG ₹6600 2022-05-26 Buy
TCI Chemicals (India) F1173 Fangchinoline 100MG ₹13400 2022-05-26 Buy

Properties

Melting point :240~242℃
Boiling point :709.7±60.0 °C(Predicted)
Density :1.204±0.06 g/cm3(Predicted)
storage temp. :4°C, protect from light
solubility :Soluble in chloroform and methanol;
pka :9.38±0.20(Predicted)
form :powder to crystal
color :White to Orange to Green
Water Solubility :slightly soluble in water

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

Fangchinoline is an alkaloid that has been found in S. tetrandrae and has diverse biological activities, including anti-inflammatory, neuroprotective, and anticancer properties. It inhibits the activity of sheep COX and decreases IL-6-induced proliferation of MH60 mouse hybridoma cells with IC50 values of 129 and 3.7 μM, respectively. Fangchinoline (1 and 10 μM) reduces cyanide-induced increases in secreted glutamate levels and cell death in primary neonatal rat cerebellar granule neurons. It decreases proliferation of PC3 human prostate cancer cells by 63 and 86% when used at concentrations of 20 and 30 μM, respectively. Fangchinoline reduces tumor growth in a PC3 mouse xenograft model when administered at a dose of 5 mg/kg per day for 12 days.

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