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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Epigenetics >Histone Methyltransferase Inhibitors >GSK 343

GSK 343

GSK 343 Structure
  • ₹14267.35 - ₹58054.48
  • Product name: GSK 343
  • CAS: 1346704-33-3
  • MF: C31H39N7O2
  • MW: 541.69
  • EINECS:
  • MDL Number:MFCD25563250
  • Synonyms:1H-Indazole-4-carboxamide, N-[(1,2-dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[2-(4-methyl-1-piperazinyl)-4-pyridinyl]-;1-(1-Methylethyl)-N-[(6-methyl-2-oxo-4-propyl-1,2-dihydro-3-pyridinyl)methyl]-6-[2-(4-methyl-1-piperazinyl)-4-pyridinyl]-1H-indazole-4-carboxamide GSK343;GSK 343;GSK343;GSK-343;GSK-343/GSK343;1-(1-Methylethyl)-N-[(6-Methyl-2-oxo-4-propyl-1,2-dihydro-3-pyridinyl)Methyl]-6-[2-(4-Methyl-1-piperazinyl)-4-pyridinyl]-1H-indazole-4-carboxaMide;N-[(1,2-Dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[2-(4-methyl-1-piperazinyl)-4-py
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0766
  • Product descriptionGSK343 ≥98% (HPLC)
  • Packaging5MG
  • Price₹14267.35
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0766
  • Product descriptionGSK343 ≥98% (HPLC)
  • Packaging25MG
  • Price₹58054.48
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML0766 GSK343 ≥98% (HPLC) 5MG ₹14267.35 2022-06-14 Buy
Sigma-Aldrich(India) SML0766 GSK343 ≥98% (HPLC) 25MG ₹58054.48 2022-06-14 Buy

Properties

Boiling point :797.4±60.0 °C(Predicted)
Density :1.26±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble15mg/mL, clear
form :powder
pka :11.84±0.10(Predicted)
color :, white to beige to brown
InChIKey :ULNXAWLQFZMIHX-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:

Description

GSK343 is a potent and selective EZH2 inhibitor with IC50 of 4 nM in a cell-free assay, showing 60 fold selectivity against EZH1, and >1000 fold selectivity against other histone methyltransferases.

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