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GW 627368X

GW 627368X Structure
  • ₹0
  • Product name: GW 627368X
  • CAS: 439288-66-1
  • MF: C30H28N2O6S
  • MW: 544.62
  • EINECS:
  • MDL Number:MFCD12912327
  • Synonyms:GW 627368X;GW 627368;4-(4,9-Diethoxy-1,3-dihydro-1-oxo-2H-benz[f]isoindol-2-yl)-N-(phenylsulfonyl)benzeneacetamide;2-[4-(4,9-Diethoxy-1-oxo-1,3-dihydro-2H-benzo[f]isoindol-2-yl)phenyl]-N-(phenylsulfonyl)acetamide;GW 627368;GW-627368;GW627368;GW-627368X;GW627368X;GW 627368X;CS-1654;GW627368(GW627368X);N-(benzenesulfonyl)-2-[4-(4,9-diethoxy-3-oxo-1H-benzo[f]isoindol-2-yl)phenyl]acetamide
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Density :1.327±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO : 100 mg/mL (183.61 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form :Powder
pka :5.25±0.10(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

GW 627368X is a selective and potent competitive antagonist of the EP4 receptor with additional human TP receptor affinity. In competition radioligand bioassays, GW 627368X had affinity for human EP4 and TP receptors with Ki values of 100 nM and 158 nM, respectively. Affinity for all other human prostanoid receptors is >5.0 μM. In human washed platelets, GW 627368X produced 100% inhibition of U-46619 (EC100)-induced aggregation at a concentration of 10 μM. The effects of prostaglandin E2 (PGE2) are transduced by at least four different receptors designated EP1, EP2, EP3, and EP4.

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Suppliers and manufacturers

career henan chemical co
GW 627368X
₹7.00 /1KG
GW 627368X CAS:439288-66-1
ATK CHEMICAL COMPANY LIMITED
BOC Sciences
TargetMol Chemicals Inc.
Zhejiang J&C Biological Technology Co.,Limited
Alfa Chemistry
InvivoChem
Nantong HI-FUTURE Biology Co., Ltd.
ShenZhen Trendseen Biological Technology Co.,Ltd.
Aladdin Scientific