Irbesartan
|
- ₹5500 - ₹38017.4
- Product name: Irbesartan
- CAS: 138402-11-6
- MF: C25H28N6O
- MW: 428.53
- EINECS:604-078-2
- MDL Number:MFCD00864464
- Synonyms:2-BUTYL-3-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,3-DIAZASPIRO[4.4]NON-1-EN-4-ONE;IRBESARTAN;BMS-186295;APROVEL;1,3-Diazaspiro[4.4]non-1-en-4-one, 2-butyl-3-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-;2-Isopropryl-4-methylthiazole;2-butyl-3-[[4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one;2-butyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one
5 prices
Selected condition：
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 10MG
- 50MG
- 1G
- 5G
- ManufacturerTCI Chemicals (India)
- Product numberI0859
- Product descriptionIrbesartan
- Packaging1G
- Price₹5500
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberI0859
- Product descriptionIrbesartan
- Packaging5G
- Price₹6900
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberPHR1443
- Product descriptionIrbesartan Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging1G
- Price₹9103.83
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberI2286
- Product descriptionIrbesartan ≥98% (HPLC), powder
- Packaging10MG
- Price₹9428.58
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberI2286
- Product descriptionIrbesartan ≥98% (HPLC), powder
- Packaging50MG
- Price₹38017.4
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | I0859 | Irbesartan | 1G | ₹5500 | 2022-05-26 | Buy |
| TCI Chemicals (India) | I0859 | Irbesartan | 5G | ₹6900 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | PHR1443 | Irbesartan Pharmaceutical Secondary Standard; Certified Reference Material | 1G | ₹9103.83 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | I2286 | Irbesartan ≥98% (HPLC), powder | 10MG | ₹9428.58 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | I2286 | Irbesartan ≥98% (HPLC), powder | 50MG | ₹38017.4 | 2022-06-14 | Buy |
Properties
Melting point :180-181°C
Boiling point :648.6±65.0 °C(Predicted)
Density :1.30±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >25mg/mL
pka :4.16±0.10(Predicted)
form :powder
color :white to off-white
Merck :14,5083
BCS Class :2
CAS DataBase Reference :138402-11-6(CAS DataBase Reference)
EPA Substance Registry System :1,3-Diazaspiro[4.4]non-1-en-4-one, 2-butyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]- (138402-11-6)
Boiling point :648.6±65.0 °C(Predicted)
Density :1.30±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >25mg/mL
pka :4.16±0.10(Predicted)
form :powder
color :white to off-white
Merck :14,5083
BCS Class :2
CAS DataBase Reference :138402-11-6(CAS DataBase Reference)
EPA Substance Registry System :1,3-Diazaspiro[4.4]non-1-en-4-one, 2-butyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]- (138402-11-6)
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
Angiotensin II receptor blockers (ARBs) act as cardioprotective agents that are effective in hypertension, left ventricular hypertrophy, postmyocardial infarction, and heart failure. Irbesartan is an ARB with a high affinity for the AT1 receptor (Ki = 2.7 nM) and exceptionally high bioavailability (60-80%). It is an insurmountable antagonist of AT1, as its antagonism of this receptor cannot be overcome by increasing concentrations of angiotensin II. Irbesartan effectively reduces blood pressure alone but may also be used in combination with a diuretic, such as hydrochlorothiazide. As angiotensin II contributes in diverse ways to endothelial dysfunction, irbesartan and other ARBs directly protect the vascular endothelium. Other pathologies, including diabetes and kidney disease, also benefit from the cardiovascular and endothelial protective actions of ARBs like irbesartan.Related product price
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