JERVINE
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- ₹9900 - ₹18272.6
- Product name: JERVINE
- CAS: 469-59-0
- MF: C27H39NO3
- MW: 425.6
- EINECS:207-417-9
- MDL Number:MFCD01684066
- Synonyms:Spiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-11(1H)-one,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexadecahydro-3-hydroxy-3',6',10,11b-tetraMethyl-,(2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-;17,23-epoxy-3-hydroxy-,(3-beta,23-beta)-veratraman-11-on ;17,23-epoxy-3-hydroxy-,(3beta,23beta)-veratraman-11-on ;4’,5’,6,6’,6a,6b,7,7’,7’a,8,11a,11b-hexadecahydro-3-hydroxy-3’,6’,10,11b-tetra ;Iervin;(2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexadecahydro-3-hydroxy-3',6',10,11b-tetramethyl-Spiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-11(1H)-one;jerwiny ;Spiro(9H-benzo(a)fluorene-9,2'(3'H)-furo(3,2-b)-pyridin)-11(1H)-one,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexadecahydro-3-hydroxy-3',6',10,11b-tetramethyl-
3 prices
Selected condition：
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 1MG
- 10MG
- ManufacturerTCI Chemicals (India)
- Product numberJ0009
- Product descriptionJervine
- Packaging10MG
- Price₹9900
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number420210
- Product descriptionJervine - CAS 469-59-0 - Calbiochem A cell-permeable steroidal alkaloid similar to cyclopamine that displays teratogenic effects and induces cyclopia by blocking Sonic Hedgehog signaling
- Packaging1MG
- Price₹15469.99
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberJ4145
- Product descriptionJervine ≥98% (HPLC), powder
- Packaging1MG
- Price₹18272.6
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | J0009 | Jervine | 10MG | ₹9900 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | 420210 | Jervine - CAS 469-59-0 - Calbiochem A cell-permeable steroidal alkaloid similar to cyclopamine that displays teratogenic effects and induces cyclopia by blocking Sonic Hedgehog signaling | 1MG | ₹15469.99 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | J4145 | Jervine ≥98% (HPLC), powder | 1MG | ₹18272.6 | 2022-06-14 | Buy |
Properties
Melting point :242- 244°C
alpha :D20 -150° (ethanol) (Saito); D20 -167.6° (chloroform) (Poethke)
Boiling point :541.31°C (rough estimate)
Density :1.18±0.1 g/cm3 (20 ºC 760 Torr)
refractive index :1.6400 (estimate)
storage temp. :−20°C
solubility :methanol: >2 mg/mL
form :solid
pka :14.98±0.70(Predicted)
color :White
λmax :250nm(lit.)
Merck :14,5264
Stability :Store in Freezer at - 20°C
alpha :D20 -150° (ethanol) (Saito); D20 -167.6° (chloroform) (Poethke)
Boiling point :541.31°C (rough estimate)
Density :1.18±0.1 g/cm3 (20 ºC 760 Torr)
refractive index :1.6400 (estimate)
storage temp. :−20°C
solubility :methanol: >2 mg/mL
form :solid
pka :14.98±0.70(Predicted)
color :White
λmax :250nm(lit.)
Merck :14,5264
Stability :Store in Freezer at - 20°C
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
Jervine is a naturally occuring steroidal alkaloid that causes cyclopia by blocking sonic hedgehog signaling. This is derived from the Veratrum plant species. It is a close structural analog of cyclopamine which specifically inhibits the hedgehog (Hh) pathway by interaction with the hedgehog signaling protein Smo. Jervine can be used to induce abnormal morphogenesis in a number of experimental models. Jervine is an inhibitor of Smo.More related product prices
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- 329196-48-7
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Suppliers and manufacturers
TCI Chemicals (India) Pvt. Ltd.
CLEARSYNTH LABS LTD.
Chengdu GLP biotechnology Co Ltd
Chengdu Biopurify Phytochemicals Ltd.
Shaanxi Pioneer Biotech Co., Ltd .
BOC Sciences
Chongqing Chemdad Co., Ltd
Neostar United (Changzhou) Industrial Co., Ltd.
Hubei Ipure Biology Co., Ltd
