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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Cell Cycle >Chk inhibitor >LY2603618

LY2603618

LY2603618 Structure
  • ₹0
  • Product name: LY2603618
  • CAS: 911222-45-2
  • MF: C18H22BrN5O3
  • MW: 436.3
  • EINECS:
  • MDL Number:MFCD18633253
  • Synonyms:IC-83;ly2603618 IC-83;LY2603618;N-[5-Bromo-4-methyl-2-[(2S)-2-morpholinylmethoxy]phenyl]-N'-(5-methyl-2-pyrazinyl)urea;3-(5-BroMo-4-Methyl-2-[(2s)-Morpholin-2-;1-[5-broMo-4-Methyl-2-[[(2S)-Morpholin-2-yl]Methoxy]phenyl]-3-(5-Methylpyrazin-2-yl)urea;(S)-1-(5-bromo-4-methyl-2-(morpholin-2-ylmethoxy)phenyl)-3-(5-methylpyrazin-2-yl)urea;N-[5-Bromo-4-methyl-2-[(2S)-2-morpholinylmethoxy]phenyl]-N'-(5-methyl-2-pyrazinyl)urea LY 2603618
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Boiling point :503.1±50.0 °C(Predicted)
Density :1.461
storage temp. :-20°C
solubility :Soluble in DMSO (up to 10 mg/ml)
form :solid
pka :12.06±0.70(Predicted)
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS):
Signal word:
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Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
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Description

LY2603618 is a highly selective Chk1 inhibitor with potential anti-tumor activity in a cell-free assay. IC50=7 nM, showing approximately 100-fold more potent against Chk1 than against any of the other protein kinases evaluated.

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