Letrozole
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- ₹9926.53 - ₹42639.68
- Product name: Letrozole
- CAS: 112809-51-5
- MF: C17H11N5
- MW: 285.3
- EINECS:675-034-8
- MDL Number:MFCD00866241
- Synonyms:Letrozole99%;CGS-20267, Femara;letrozolex;Lelrozol;1-[BIS(4-CYANOPHENYL)METHYL]-1,2,4-TRIAZOLE;4,4'-(1H-1,2,4-Triazol-1-ylmethylene)dibenzonitrile;4,4'-(1H-1,2,4-Triazole-1-ylmethylene)bisbenzonitrile;4,4'-[(1H-1,2,4-Triazole-1-yl)methylene]dibenzonitrile
3 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 10MG
- 50MG
- 1G
- ManufacturerSigma-Aldrich(India)
- Product numberPHR1540
- Product descriptionLetrozole Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging1G
- Price₹9926.53
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberL6545
- Product descriptionLetrozole ≥98% (HPLC)
- Packaging10MG
- Price₹10532.73
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberL6545
- Product descriptionLetrozole ≥98% (HPLC)
- Packaging50MG
- Price₹42639.68
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | PHR1540 | Letrozole Pharmaceutical Secondary Standard; Certified Reference Material | 1G | ₹9926.53 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | L6545 | Letrozole ≥98% (HPLC) | 10MG | ₹10532.73 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | L6545 | Letrozole ≥98% (HPLC) | 50MG | ₹42639.68 | 2022-06-14 | Buy |
Properties
Melting point :181-183°C
Boiling point :563.5±60.0 °C(Predicted)
Density :1.21±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >50mg/mL
pka :1.52±0.11(Predicted)
form :White powder
color :white to off-white
Merck :14,5450
InChI :InChI=1S/C17H11N5/c18-9-13-1-5-15(6-2-13)17(22-12-20-11-21-22)16-7-3-14(10-19)4-8-16/h1-8,11-12,17H
InChIKey :HPJKCIUCZWXJDR-UHFFFAOYSA-N
SMILES :C(C1=CC=C(C=C1)C#N)(C1=CC=C(C=C1)C#N)N1C=NC=N1
CAS DataBase Reference :112809-51-5(CAS DataBase Reference)
Boiling point :563.5±60.0 °C(Predicted)
Density :1.21±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >50mg/mL
pka :1.52±0.11(Predicted)
form :White powder
color :white to off-white
Merck :14,5450
InChI :InChI=1S/C17H11N5/c18-9-13-1-5-15(6-2-13)17(22-12-20-11-21-22)16-7-3-14(10-19)4-8-16/h1-8,11-12,17H
InChIKey :HPJKCIUCZWXJDR-UHFFFAOYSA-N
SMILES :C(C1=CC=C(C=C1)C#N)(C1=CC=C(C=C1)C#N)N1C=NC=N1
CAS DataBase Reference :112809-51-5(CAS DataBase Reference)
Safety Information
Symbol(GHS): |
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Signal word: | Warning | ||||||||||||||
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Description
Letrozole (trade name: Femara) is an orally active nonsteroidal aromatase inhibitor. As a competitive inhibitor of the aromatase, Letrozole inhibits the conversion of androgens to estrogen (estrogen stimulates breast tissues and breast cancer reoccurrence) and gonadal steroidogenesis. It can be used for the treatment of breast cancer that is hormonally-responsive or has an unknown receptor status in postmenopausal women. Besides this, Letrozole also has some off-label use such as ovarian stimulation, pretreatment of termination of pregnancy, treatment of gynecomastia, treatment of endometriosis, and promoting spermatogenesis for male patients of nonobstructive azoospermia.More related product prices
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