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ChemicalBook > Product Catalogue >API >Synthetic Anti-infective Drugs >Antiviral drugs >Lopinavir

Lopinavir

Lopinavir Structure
  • ₹2686.2 - ₹29584.73
  • Product name: Lopinavir
  • CAS: 192725-17-0
  • MF: C37H48N4O5
  • MW: 628.81
  • EINECS:200-001-8
  • MDL Number:MFCD22628840
  • Synonyms:LOPINAVIR;A 157378.0;ABT 378;Aluviran;Koletr;(aS)-N-[(1S,3S,4S)-4-[[2-(2,6-Dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2-oxo-1(2H)-Pyrimidineacetamide;Koletra;(2S)-N-[(2S,4S,5S)-5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenyl-hexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide
Price3 Properties Safety Information Description
3 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • 1G
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1222
  • Product descriptionLopinavir ≥98% (HPLC)
  • Packaging10MG
  • Price₹2686.2
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1222
  • Product descriptionLopinavir ≥98% (HPLC)
  • Packaging50MG
  • Price₹6882
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1927
  • Product descriptionLopinavir Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹29584.73
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML1222 Lopinavir ≥98% (HPLC) 10MG ₹2686.2 2022-06-14 Buy
Sigma-Aldrich(India) SML1222 Lopinavir ≥98% (HPLC) 50MG ₹6882 2022-06-14 Buy
Sigma-Aldrich(India) PHR1927 Lopinavir Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹29584.73 2022-06-14 Buy

Properties

Melting point :255.2-260.6 °F (124—127°C)
Boiling point :924.1±65.0 °C(Predicted)
Density :1.163±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
pka :13.89±0.46(Predicted)
form :powder
color :white to beige
optical activity :[α]/D -20 to -27°, c = 0.4 in methanol
Stability :Hygroscopic
CAS DataBase Reference :192725-17-0(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P314 Get medical advice/attention if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P501 Dispose of contents/container to..…

Description

Lopinavir is a potent inhibitor of HIV-1 protease (Ki = 1.3 pM) that blocks the replication of laboratory and clinical strains of HIV-1 (EC50 = 6-17 nM) and is effective against certain mutant strains.

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Suppliers and manufacturers

J S LABS SEUTIC SUJALAM CHEMICALS TYNDAL LABS PVT LTD Hetero Drugs Limited Venture Pharmaceuticals pvt ltd HRV Global Life Sciences Aurobindo Pharma Limited Cipla Ltd Amara Labs Pvt Ltd