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ChemicalBook > Product Catalogue >API >Antiparasitic drugs >Antiamoebic and anti-trichomoniasis drugs >Lycorine hydrochloride

Lycorine hydrochloride

Lycorine hydrochloride Structure
  • ₹29779.58
  • Product name: Lycorine hydrochloride
  • CAS: 2188-68-3
  • MF: C16H17NO4
  • MW: 287.31
  • EINECS:
  • MDL Number:MFCD00243111
  • Synonyms:Lycorine Hydrochloride98%;Licorin hydrochloride;Hydrochloric Lycorine;LYCORIN;(-)-LYCORINE;LYCORINE;NARCISSIN(P);(1S,2S,12BS,12CS)-1,2,4,5,12B,12C-HEXAHYDRO-7H-[1,3]DIOXOLO[4,5-J]PYRROLO[3,2,1-DE]PHENANTHRIDINE-1,2-DIOL
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Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 20MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberL5139
  • Product descriptionLycorine hydrochloride ≥98% (TLC), powder
  • Packaging20MG
  • Price₹29779.58
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) L5139 Lycorine hydrochloride ≥98% (TLC), powder 20MG ₹29779.58 2022-06-14 Buy

Properties

Melting point :206 °C
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :Soluble in water (15 mg/ml)
form :powder
color :White to off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in water may be stored at -20°C for up to 1 month.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Lycorine (2188-68-3) arrests cell cycle at G2/M phase and induces apoptosis in tumor cells.1 Inhibits human enterovirus 71 replication by blocking elongation of the viral polyprotein during translation and reduces viral cytopathic effects in mice.2 Dose-dependently extends the circadian period length in mammalian cells by enhancing Bmal1 transcription.3 Selectively inhibits human ovarian cancer cell proliferation and neovascularization (IC50=1.2 μM).4?A potent SREBF chaperone (SCAP) degrader (Kd=15.24 nM) which acts via an autophagy-independent lysosomal pathway.5

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