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MONACOLIN J

MONACOLIN J Structure
  • ₹0
  • Product name: MONACOLIN J
  • CAS: 79952-42-4
  • MF: C19H28O4
  • MW: 320.42322
  • EINECS:
  • MDL Number:MFCD09832923
  • Synonyms:6(R)-[2-(8(S)-Hydroxy]-2(S),6(R)-dimethyl-1,2,6,7,8,8a(R)-hexahydro-1(S)-naphthyl]ethyl-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-one;(4R,6R)-;SiMvastatin Lactone Diol;Lovastatin Lactone Diol;Lovastatin Diol Lactone;monacolin J;(4R,6R)-4-Hydroxy-6-(2-((1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)ethyl)tetrahydro-2H-pyran-2-one;Simvastatin EP Impurity H
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :50-53°C
Boiling point :535.7±50.0 °C(Predicted)
Density :1.17±0.1 g/cm3(Predicted)
storage temp. :Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility :Chloroform (Slightly), DMF, DMSO, Methanol (Slightly)
form :Solid
pka :13.49±0.40(Predicted)
color :White to Pale Yellow
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Monacolin J is a Simvastatin intermediate; Lovastatin analog has the activities of decreasing blood cholesterol and low-d. lipoprotein, can be used to preparation hypolipidemic medicine.

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