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ChemicalBook > Product Catalogue >API >Circulatory system drugs >Lipid regulating drugs >Lovastatin

Lovastatin

Lovastatin Structure
  • ₹8042.98 - ₹22440.23
  • Product name: Lovastatin
  • CAS: 75330-75-5
  • MF: C24H36O5
  • MW: 404.54
  • EINECS:616-212-7
  • MDL Number:MFCD00072164
  • Synonyms:SiMvastatin EP IMpurity E;8-[2-(4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-1-nap;6alpha-Methylcompactin Mevinolin Monacolin K;)ethyl]-1-naphthalenylester ;[1s-[1alpha(r*),3alpha,7beta,8beta(2s*,4s*),8abeta]]-2-methylbutanoicacid1,2, ;1,2,6,7,8,8a-hexahydro-beta,delta-dihydroxy-2,6-dimethyl-8-(2-methyl-1-oxobuty ;2-methyl-,1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(tetrahydro-butanoicaci ;3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2h-pyran-2-yl
6 prices
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Brand

  • Sigma-Aldrich
  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 25MG
  • 1G
  • 5G
  • 25G
  • ManufacturerSigma-Aldrich
  • Product number438185
  • Product descriptionLovastatin - CAS 75330-75-5 - Calbiochem Lovastatin, CAS 75330-75-5, is an anti-hypercholesterolemic agent that inhibits the activity of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase.
  • Packaging25MG
  • Price₹20710
  • Updated2022-06-14
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberL0214
  • Product descriptionLovastatin
  • Packaging5G
  • Price₹9000
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberL0214
  • Product descriptionLovastatin
  • Packaging25G
  • Price₹13200
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1285
  • Product descriptionLovastatin Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹8042.98
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number438185
  • Product descriptionLovastatin - CAS 75330-75-5 - Calbiochem Lovastatin, CAS 75330-75-5, is an anti-hypercholesterolemic agent that inhibits the activity of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reduct
  • Packaging25MG
  • Price₹20710
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM2147
  • Product descriptionMevinolin from Aspergillus sp. ≥98% (HPLC)
  • Packaging25MG
  • Price₹22440.23
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich 438185 Lovastatin - CAS 75330-75-5 - Calbiochem Lovastatin, CAS 75330-75-5, is an anti-hypercholesterolemic agent that inhibits the activity of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase. 25MG ₹20710 2022-06-14 Buy
TCI Chemicals (India) L0214 Lovastatin 5G ₹9000 2022-05-26 Buy
TCI Chemicals (India) L0214 Lovastatin 25G ₹13200 2022-05-26 Buy
Sigma-Aldrich(India) PHR1285 Lovastatin Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹8042.98 2022-06-14 Buy
Sigma-Aldrich(India) 438185 Lovastatin - CAS 75330-75-5 - Calbiochem Lovastatin, CAS 75330-75-5, is an anti-hypercholesterolemic agent that inhibits the activity of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reduct 25MG ₹20710 2022-06-14 Buy
Sigma-Aldrich(India) M2147 Mevinolin from Aspergillus sp. ≥98% (HPLC) 25MG ₹22440.23 2022-06-14 Buy

Properties

Melting point :175°C
alpha :D25 +323° (c = 0.5 g in 100 ml acetonitrile)
Boiling point :559.2±50.0 °C(Predicted)
Density :1.12±0.1 g/cm3(Predicted)
vapor pressure :0Pa at 25℃
refractive index :320 ° (C=0.5, CH3CN)
storage temp. :-20°C
solubility :ethanol: soluble9.80-10.20mg/mL, clear, colorless to faintly yellow
form :White to off-white powder
pka :13.49±0.40(Predicted)
color :White
Water Solubility :0.0004 mg/mL at 25 ºC
Merck :14,5586
BCS Class :2
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
LogP :4.260
CAS DataBase Reference :75330-75-5(CAS DataBase Reference)
EPA Substance Registry System :Lovastatin (75330-75-5)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Lovastatin is a cholesterol lowering drug and competitive inhibitor of HMG-CoA reductase, a rate limiting enzyme in cholesterol synthesis. Blocks the production of mevalonate, a critical compound in the production of cholesterol and isoprenoids. It increases cellular resistance to anticancer agents such as doxorubicin and induces apoptosis in myeloma cells. It causes cell cycle arrest in G1 and G2/M phases.

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