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MYRIOCIN

MYRIOCIN Structure
  • ₹7934.73 - ₹31197.65
  • Product name: MYRIOCIN
  • CAS: 35891-70-4
  • MF: C21H39NO6
  • MW: 401.54
  • EINECS:636-862-5
  • MDL Number:MFCD01632772
  • Synonyms:MYRIOCIN;MYRIOCIN, MYCELIA STERILIA;THERMOZYMOCIDIN;6e))-4s* ;6-eicosenoicacid,2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-,(2s-(2r*,3s ;[2S,3R,4R,6E]-2-AMINO-3,4-DIHYDROXY-2-[HYDROXYMETHYL]-14-OXO-6-EICOSENOIC ACID;[2S,3R,4R]-(E)-2-AMINO-3,4-DIHYDROXY-2-[HYDROXYMETHYL]-14-OXO-6-EICOSENOIC ACID;ISP-I
3 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberM1177
  • Product descriptionMyriocin from Mycelia sterilia ≥98% (HPLC), powder
  • Packaging5MG
  • Price₹7934.73
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number476300
  • Product descriptionMyriocin, Mycelia sterilia - CAS 35891-70-4 - Calbiochem A potent immunosuppressant.
  • Packaging5MG
  • Price₹14100
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM1177
  • Product descriptionMyriocin from Mycelia sterilia ≥98% (HPLC), powder
  • Packaging25MG
  • Price₹31197.65
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) M1177 Myriocin from Mycelia sterilia ≥98% (HPLC), powder 5MG ₹7934.73 2022-06-14 Buy
Sigma-Aldrich(India) 476300 Myriocin, Mycelia sterilia - CAS 35891-70-4 - Calbiochem A potent immunosuppressant. 5MG ₹14100 2022-06-14 Buy
Sigma-Aldrich(India) M1177 Myriocin from Mycelia sterilia ≥98% (HPLC), powder 25MG ₹31197.65 2022-06-14 Buy

Properties

Melting point :170-172℃
Boiling point :636.7±55.0 °C(Predicted)
Density :1.123±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :methanol: 2 mg/mL
form :powder
pka :1.79±0.50(Predicted)
color :off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 4 months.
InChIKey :ZZIKIHCNFWXKDY-XFXZXTDPSA-N
CAS DataBase Reference :35891-70-4

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Myriocin is an amino fatty acid antibiotic derived from certain thermophylic fungi, in this case Mycelia sterilia. It is a potent immunosuppressant having 10- to 100-fold more activity than cyclosporin A. Myriocin is a potent inhibitor of serine palmitoyltransferase (Ki = 0.28 nM), the enzyme that catalyzes the first step of sphingolipid biosynthesis. It disrupts substratum adhesion of melanoma cells. It also suppresses cell proliferation in the murine cytotoxic T cell line CTLL-2 (IC50 = 15 nM) via apoptosis. Myriocin suppresses replication of the hepatitis C virus in a murine model.

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