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ChemicalBook > Product Catalogue >Natural Products >Terpenes >Madecassic acid

Madecassic acid

Madecassic acid Structure
  • ₹0
  • Product name: Madecassic acid
  • CAS: 18449-41-7
  • MF: C30H48O6
  • MW: 504.71
  • EINECS:240-851-7
  • MDL Number:MFCD29048539
  • Synonyms:(2alpha,3beta,4alpha,6beta)-2,3,6,23-tetrahydroxy-urs-12-en-28-oic acid;MADECASSIC ACID;Urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2.alpha.,3.beta.,4.alpha.,6.beta.)-;(1S,2R,4aS,6aS,6aS,6bR,8R,8aR,9R,10R,11R,12aR,14bR)-8,10,11-trihydroxy -9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,1 1,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid;Hydroxy asiaticoside;MADECASSIC ACID(P);6BETA-HYDROXYASIATIC ACID;2α,3β,6β,23-Tetrahydroxyurs-12-en-28-oic acid
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :270°C (dec.)
Boiling point :641.7±55.0 °C(Predicted)
Density :1.23±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO (Sparingly), Methanol (Slightly, Heated)
pka :4.63±0.70(Predicted)
form :Solid
color :White to Pale Red
InChIKey :PRAUVHZJPXOEIF-MRQYELSVNA-N
LogP :4.321 (est)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P391 Collect spillage. Hazardous to the aquatic environment
P405 Store locked up.

Description

Madecassic acid is a natural triterpene first isolated from C. asiatica. It has diverse anti-inflammatory and anti-diabetic effects, blocking NF-κB activation in macrophages and altering lipid metabolism in mice, at least in part through antioxidant actions. The metabolism of madecassic acid in vivo has been described.

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