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ChemicalBook > Product Catalogue >API >Antibiotics >β-Lactamase inhibitors >Meropenem

Meropenem

Meropenem Structure
  • ₹0
  • Product name: Meropenem
  • CAS: 96036-03-2
  • MF: C17H25N3O5S
  • MW: 383.46
  • EINECS:641-424-1
  • MDL Number:MFCD00864966
  • Synonyms:(4r,5s,6s)-3-[[(3s,5s)-5-dimethylcarbamoylpyrrolidin-3-;)-3-pyrrolidinyl)thio)-6-(1-hydroxyethyl)-4-methyl-7-oxo-,(4r-(3(s*,5s*),4-al ;5-beta,6-beta(r*)))-ph ;antibioticsm7338 ;ici194660 ;MEROPENEM, USP STANDARD;MEROPENEM, USP;Meropenemanhydrous
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Boiling point :627.4±55.0 °C(Predicted)
Density :1.42±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :insoluble in EtOH; ≥19.15 mg/mL in DMSO; ≥9.88 mg/mL in H2O with ultrasonic
form :solid
pka :4.27±0.60(Predicted)
color :White to off-white
InChI :InChI=1S/C17H25N3O5S/c1-7-12-11(8(2)21)16(23)20(12)13(17(24)25)14(7)26-9-5-10(18-6-9)15(22)19(3)4/h7-12,18,21H,5-6H2,1-4H3,(H,24,25)/t7-,8-,9+,10+,11-,12-/m1/s1
InChIKey :DMJNNHOOLUXYBV-PQTSNVLCSA-N
SMILES :N12[C@@]([H])([C@@H]([C@H](O)C)C1=O)[C@@H](C)C(S[C@H]1C[C@@H](C(N(C)C)=O)NC1)=C2C(O)=O
CAS DataBase Reference :96036-03-2(CAS DataBase Reference)
EPA Substance Registry System :Meropenem (96036-03-2)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

Meropenem is an intravenous β-lactam antibiotic that is effective against Gram-positive and Gram-negative bacteria (MICs range from 0.008-0.13 μg/ml). Similar to other β-lactam antibiotics, meropenem inhibits bacterial cell wall synthesis, yet in contrast to other β-lactam antibiotics, it is highly resistant to degradation by β-lactamases.

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