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ChemicalBook > Product Catalogue >API >Hormones and the Endocrine System >Prostaglandin drugs >Misoprostol Acid

Misoprostol Acid

Misoprostol Acid  Structure
  • ₹15209.13
  • Product name: Misoprostol Acid
  • CAS: 112137-89-0
  • MF: C21H36O5
  • MW: 368.51
  • EINECS:
  • MDL Number:MFCD07772001
  • Synonyms:MISOPROSTOL FREE ACID;(+/-)-15-DEOXY-[16RS]-16-HYDROXY-16-METHYLPROSTAGLANDIN E1;(11a,13E)-11,16-Dihydroxy-16-methyl-9-oxo-prost-13-en-1-oic Acid;(-15-Deoxy-(16RS)-16-hydroxy-16-methylprogestaglandin E;MISOPROSTOL ACID;(+/-)-15-Deoxy-(16RS)-16-hydroxy-16-methylprogestaglandin E1;Misoprostol free acid,(±)-15-Deoxy-(16RS)-16-hydroxy-16-methylprostaglandin E1;Misoprostol Acid (10 mg in 1 mL Methyl Acetate)
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Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 1MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberM6932
  • Product descriptionMisoprostol free acid ≥90%
  • Packaging1MG
  • Price₹15209.13
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) M6932 Misoprostol free acid ≥90% 1MG ₹15209.13 2022-06-14 Buy

Properties

Boiling point :538.3±50.0 °C(Predicted)
Density :1.118±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Chloroform
pka :4.77±0.10(Predicted)
form :Yellow viscous oil.
color :Pale Yellow
Stability :Temperature Sensitive

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Misoprostol is a prostaglandin E1 analog with agonist activity mediated by EP2, EP3, and EP4 receptors. It has been shown to inhibit the formation of gastric lesions in rats (ED50 = 0.31 μg/kg), inhibit superoxide generation in human neutrophils (EC50 = 0.35 μM), and relax fetal rabbit ductus arteriosus (EC50 = 0.36 nM) in a concentration dependent manner. Misoprostol is commonly used in clinical medicine for the prevention of peptic ulcer disease. It has also been used in conjunction with mifepristone (RU-486; ) for the oral induction of first trimester abortion. Misoprostol contains a C-1 methyl ester and is readily absorbed and rapidly hydrolyzed in humans to the active free acid.

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