15(R)-PROSTAGLANDIN E1
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- ₹0
- Product name: 15(R)-PROSTAGLANDIN E1
- CAS: 19313-28-1
- MF: C20H36O5
- MW: 356.5
- EINECS:
- MDL Number:MFCD00135208
- Synonyms:9-OXO-11ALPHA,15S-DIHYDROXY-PROSTAN-1-OIC ACID;13,14-DIHYDROPROSTAGLANDIN E1;PGE0;13,14-Dihydroprostaglandinee1;13,14-dihydro PGE1;7-[(1R,2R,3R)-3-hydroxy-2-[(3S)-3-hydroxyoctyl]-5-oxocyclopentyl]heptanoic acid;(11R)-11α,15α-Dihydroxy-9-oxoprostan-1-oic acid;13,14-Dihydro-prostaglandin E1 (PGE0)
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Properties
Boiling point :541.4±35.0 °C(Predicted)
Density :1.075±0.06 g/cm3(Predicted)
storage temp. :Refrigerator, under inert atmosphere
solubility :Ethyl Acetate, Methanol, Tetrahydrofuran
form :Colorless to pale yellow oil
pka :4.77±0.10(Predicted)
Stability :Volatile
Density :1.075±0.06 g/cm3(Predicted)
storage temp. :Refrigerator, under inert atmosphere
solubility :Ethyl Acetate, Methanol, Tetrahydrofuran
form :Colorless to pale yellow oil
pka :4.77±0.10(Predicted)
Stability :Volatile
Safety Information
Symbol(GHS): |
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Description
13,14-dihydro Prostaglandin E1 (13,14-dihydro PGE1) is a biologically active metabolite of PGE1 with comparable potency to the parent compound. It is an inhibitor of ADP-induced platelet aggregation in human PRP and washed platelets with IC50 values of 31 and 21 nM, respectively. 13,14-dihydro PGE1 is a slightly more potent inhibitor of ADP-induced human platelet aggregation than PGE1 which has an IC50 value of 40 nM. Also, 13,14-dihydro PGE1 was shown to activate adenylate cyclase in NCB-20 hybrid cells with a Kact value of 668 nM.Related product price
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Suppliers and manufacturers
Aladdin Scientific
Nantong Hanfang Biotechnology Co. , Ltd.
TargetMol Chemicals Inc.
MP Biomedicals, Inc.
Biomol Feinchemikalien GmbH
BIOMOL INTERNATIONAL, LP
Service Chemical Inc.
3B Pharmachem (Wuhan) International Co.,Ltd.
Shanghai Synchem Pharma Co., ltd
Shenzhen Polymeri Biochemical Technology Co., Ltd.