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13,14-DIHYDRO-15-KETO PROSTAGLANDIN E1

13,14-DIHYDRO-15-KETO PROSTAGLANDIN E1 Structure
  • ₹0
  • Product name: 13,14-DIHYDRO-15-KETO PROSTAGLANDIN E1
  • CAS: 5094-14-4
  • MF: C20H34O5
  • MW: 354.49
  • EINECS:
  • MDL Number:MFCD00135210
  • Synonyms:13,14-DIHYDRO-15-KETO PROSTAGLANDIN E1;9,15-DIOXO-11ALPHA-HYDROXY-PROSTAN-1-OIC ACID;CDUVSQMTLOYKTR-ZHALLVOQSA-N;13,14-dihydro-15-keto PGE1;9,15-dioxo-11α-hydroxy-prostan-1-oic acid;U 21002;Prostan-1-oic acid, 11-hydroxy-9,15-dioxo-, (11α)-;15-Keto Prostaglandin E0 DISCONTINUED, OFFER K202056
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Properties

Boiling point :537.2±35.0 °C(Predicted)
Density :1.072±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly), Methanol (Slightly), THF (Slightly)
form :Oil
pka :4.77±0.10(Predicted)
color :Dark Yellow

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

13,14-dihydro-15-keto Prostaglandin E1 (PGE1) is a metabolite of PGE1 with much reduced biological activity. Steady state plasma concentrations are about 10 pg/ml. 13,14-dihydro-15-keto PGE1 is a weak inhibitor of ADP-induced platelet aggregation in human PRP and washed platelets with IC50 values of 54 and 200 μM, respectively, compared to PGE1 which has an IC50 of 40 nM.