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ChemicalBook > Product Catalogue >API >Antineoplastic agents >Alkylating antineoplastic >Mizolastine

Mizolastine

Mizolastine Structure
  • ₹8300 - ₹15000
  • Product name: Mizolastine
  • CAS: 108612-45-9
  • MF: C24H25FN6O
  • MW: 432.49
  • EINECS:1308068-626-2
  • MDL Number:MFCD23140913
  • Synonyms:4(1h)-pyrimidinone,2-((1-(1-((4-fluorophenyl)methyl)-1h-benzimidazol-2-yl)-4-p ;iperidinyl)methylamino)- ;2-[[1-[1-[(4-fluorophenyl)methyl]benzoimidazol-2-yl]-4-piperidyl]-methyl-amino]-3h-pyrimidin-4-one;MIZOLASTINE;2-[[1-[1-[(4-fluorophenyl)methyl]-1H-benzimidazol-2-yl]-4-piperidinyl]methylamino]-4(1H)-pyrimidinone;Mizolastine HCl;2-[[1-[1-(4-fluorobenzyl)benzimidazol-2-yl]-4-piperidyl]-methyl-amino]-1H-pyrimidin-6-one;2-[[1-[1-[(4-fluorophenyl)methyl]benzimidazol-2-yl]piperidin-4-yl]-methyl-amino]-1H-pyrimidin-6-one
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • TCI Chemicals (India)

Package

  • 1G
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberM2756
  • Product descriptionMizolastine
  • Packaging1G
  • Price₹8300
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberM2756
  • Product descriptionMizolastine
  • Packaging5G
  • Price₹15000
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) M2756 Mizolastine 1G ₹8300 2022-05-26 Buy
TCI Chemicals (India) M2756 Mizolastine 5G ₹15000 2022-05-26 Buy

Properties

Melting point :217°
Density :1.34±0.1 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :Chloroform (Slightly, Heated), DMSO, Methanol (Slightly, Heated)
form :Solid
pka :9.73±0.40(Predicted)
color :White
Merck :14,6221

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning GHS hazard pictograms P280,P302+P352, P312, P322, P363,P501
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P322 Specific measures (see …on this label).
P330 Rinse mouth.
P363 Wash contaminated clothing before reuse.
P501 Dispose of contents/container to..…

Description

Mizolastine was marketed in Germany and Switzerland as Mizollen for the symptomatic relief of seasonal and perennial allergic rhinoconjunctivitis and urticaria. Mizolastine is a new long-acting, orally active antihistaminic agent with a rapid onset of action ; the two most recent H1 antagonists launched were fexofenadine, metabolite of terfenadine (Sepracor, 1996) and Olopatadine (Kyowa Hakko, 1997). Mizolastine can be prepared in 2 steps from 2-chloro 1- (4-fluorobenzyl)benzimidazole by successive condensations of appropriate amine and thioether. Mizolastine selectively blocks the peripheral H1 receptors (but not the serotonergic, noradrenergic, muscarinic receptors) with a minimal occupancy of brain receptors, and therefore does not elicit any sedative effects. Moreover, Mizolastine does not produce cardiac rhythm disorders which have been associated with certain non-sedating antihistamines in humans.

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Suppliers and manufacturers

Ralington Pharma Bal Pharma Limited Rivashaa Agrotech Biopharma Pvt. Ltd. OCEAN TRADING CORPORATION Medilink Pharmachem TCI Chemicals (India) Pvt. Ltd. Pharmaffiliates Analytics and Synthetics P. Ltd Angle Biopharma A.J Chemicals CLEARSYNTH LABS LTD.